A cohort of 60 mouse-intraductal patient-derived xenograft models of primary invasive breast cancer was developed to develop neoadjuvant treatments.
Category: 8. Health
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Patient-derived xenograft models of primary breast cancer for preclinical evaluation of neoadjuvant therapies | Science Translational Medicine
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Selective targeting of mutant huntingtin intron 1 improves rescue provided by antisense oligonucleotides in Huntington’s disease mice | Science Translational Medicine
Selective lowering of mHtt and Htt1a is superior to nonselective lowering of Htt in rescuing aggregate formation and transcriptional dysregulation.
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Amyloid-β as a target to suppress tonic PTH hypersecretion in hyperparathyroidism due to vitamin D deficiency | Science Translational Medicine
Blocking aberrant signaling of Aβ, GABAB1R/CaSR dimer, and Tau suppresses tonic PTH hypersecretion in hyperparathyroidism due to vitamin D deficiency.
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What’s the equivalent of a wheelchair for a person with schizophrenia? How psychiatric rehabilitation brings community into care
Imagine your dream is to get a job at the local library. You have a love for people and for books. You also have schizophrenia, a psychiatric disability that makes life in the community more challenging.
You often have extreme…
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Millions of CT scans are done every year – most leave important data behind
Recently, a patient came to the hospital where I work with a persistent cough. Their doctor had ordered a CT scan – a type of imaging that creates detailed cross-sectional pictures of the body’s interior – to look for pneumonia or…
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Prototype breath tests spot bacterial infections in minutes
Infectious diseases are a major cause of death worldwide, and diagnosing bacterial infections remains a challenge in medicine. And doing so reliably is more important than ever, given the increasing frequency of antibiotic resistance. Now,…
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Adults With ADHD Experience Sleep-Like Brain Waves While Awake
Attention deficit hyperactivity disorder (ADHD) affects almost 7 percent of adults worldwide, but despite being a common neurological disorder, there’s still a lot we don’t know about it. For example, what’s going on in the brains of people…
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How Sleep Memory Science Powers Better Focus and Stronger Memory
Sleep is not just downtime for the body; it is active maintenance time for the brain. The relationship between sleep and brain health shapes how well a person can think, focus, manage emotions, and remember important…
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Top Brain-Boosting Foods for Memory and Focus: Power Your Brain Naturally
Strong memory and focus rely heavily on what you eat each day. Brain health foods provide essential nutrients like omega-3 fatty acids and antioxidants that support long-term cognitive function. A well-planned memory diet can help…
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Processed Food Health Risks and How Ultra-Processed Diets Quietly Damage Long-Term Health
Ultra-processed foods have become everyday staples, yet the long-term processed food health risks are often underestimated. From ready meals and packaged snacks to sugary drinks and fast food, these products are designed for taste…
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