Brigatinib enhances PARPi response in HGSOC by disrupting adaptive survival of malignant cells by dual FAK and EPHA2 inhibition.
Category: 8. Health
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Dual FAK and EPHA2 targeting by brigatinib tackles PARP inhibitor adaptive survival response in high-grade serous ovarian cancer | Science Translational Medicine
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Erratum for the Research Article “Single immunizations of self-amplifying or non-replicating mRNA-LNP vaccines control HPV-associated tumors in mice” by J. Ramos da Silva et al. | Science Translational Medicine
In the Research Article “Single immunizations of self-amplifying or non-replicating mRNA-LNP vaccines control HPV-associated tumors in mice” by J. Ramos da Silva et al., the image for the day 21 gDE7 U sa-mRNA-LNP group in Fig. 6B was…
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Endothelial cell–released CD93 contributes to podocyte injury in idiopathic nephrotic syndrome | Science Translational Medicine
Soluble CD93 contributes to podocyte injury, and CD93 blockade emerges as a candidate therapeutic target in INS.
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Reddit and TikTok – with the help of AI
When you think of tools for studying substance use and addiction, a social media site like Reddit, TikTok or YouTube probably isn’t the first thing that comes to mind. Yet the stories shared on social media platforms are offering…
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The aggressive use of antibiotics could fuel mood disorders and anxiety
Antibiotics (ABs) are among the most used pharmaceutical drugs worldwide, as they are currently the most effective medicines for the treatment of bacterial infections. An excessive use of these drugs, however, can damage the gut microbiota, the…
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Double threat: HIV and hepatitis B co-infection increases risk of kidney dysfunction
A new 10-year regional study reveals that adults living with both HIV and hepatitis B virus across the Asia-Pacific face substantially higher risks of kidney dysfunction than those living with HIV alone.
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Rapid response teams expedite stroke imaging, treatment
A streamlined, nurse-led response for hospitalized patients experiencing an acute stroke at a Texas academic medical center improved time from symptom discovery to imaging and treatment, which is associated with better outcomes.
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Death and doctors: New study looks at medical student education on end-of-life care
Doctors encounter death and dying significantly more than most people. It’s the price of saving lives and helping people.
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Diabetes risk not associated with timing or type of menopause
Women aged younger than 45 years who experience menopause are at a higher risk of coronary heart disease and stroke. However, despite such diabetes-related risk factors as increased fat and insulin resistance occurring during menopause, a new…
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Pregnancy-related high blood pressure varies among Asian, Pacific Islander subgroups, study finds
The risk of pregnancy-related high blood pressure varies markedly among subgroups of Asian American, Native Hawaiian and Pacific Islander people, highlighting the need for tailored prevention and treatment, according to research published in the…
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