Analyses of longitudinal plasma samples from patients with trauma identify biological states that determine divergent thromboinflammatory outcomes.
Category: 8. Health
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Multiomic analyses of longitudinal plasma samples identify thromboinflammation endotypes and trajectories in patients with trauma | Science Translational Medicine
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The TUB variant impairs leptin sensitivity and AgRP neuronal response, leading to obesity | Science Translational Medicine
Rare human TUB variants impair leptin sensitivity through disruption of STAT3 activation, leading to hyperphagic obesity.
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Erratum for the Research Article “A rationally designed cocktail of nanobodies elicited by heterologous vaccination confers protection against SFTSV in preclinical models” | Science Translational Medicine
In the Research Article “A rationally designed cocktail of nanobodies elicited by heterologous vaccination confers protection against SFTSV in preclinical models” by X. Wu et al., Fig. 4E was erroneously duplicated as Fig. 4H. Figure 4H has…
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Lactylation fuels nucleotide biosynthesis and facilitates deuterium metabolic imaging of tumor proliferation in preclinical models of H3K27M-mutant gliomas | Science Translational Medicine
H3K27M-driven lactylation facilitates nucleotide biosynthesis, an effect that can be exploited for metabolic imaging of disease progression in DMGs.
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Levetiracetam prevents Aβ production through SV2a-dependent modulation of APP processing in Alzheimer’s disease models | Science Translational Medicine
Levetiracetam prevents Aβ production by reducing synaptic vesicle cycling and restoring APP nonamyloidogenic processing.
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Parenteral vaccination with an adjuvanted mRNA vaccine induces protective mucosal immunity against rotavirus in neonatal mice | Science Translational Medicine
An Am80-loaded mRNA-LNP vaccine against rotavirus elicits intestinal mucosal immunity in mice and pigs and protects neonatal mice against infection.
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Why is US health care still the most expensive in the world after decades of cost-cutting initiatives?
In announcing its “Great Healthcare Plan” in January 2026, the Trump administration became the latest in a long history of efforts by the U.S. government to rein in the soaring cost of health care.
As a physician and professor studying…
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Cancer Warning: Nearly Every Hair Extension Tested Contained Toxic Chemicals
A groundbreaking study reveals that many popular hair extensions may carry hidden cancer-linked chemicals — and sparks calls for urgent regulation. A sweeping new investigation from Silent Spring Institute has uncovered dozens of potentially…
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Why Exercising May Not Help You Lose Weight
New research shows our bodies might compensate for all that hard work
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Bob Wachter On Healthcare’s “Giant Leap,” Taken One Step At A Time
Bob Wachter’s new book explains how AI is reshaping healthcare. Here, I reflect on what it gets right, what it leaves open, and why progress comes one step at a time.
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