A dual-action peptide that activates MST1 can expand and stabilize murine and human regulatory T cells to induce therapeutic immune tolerance.
Category: 8. Health
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A peptide immunomodulator activates MST1 to expand and stabilize murine and human regulatory T cells for immune tolerance | Science Translational Medicine
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Epigenetic reactivation of the tumor suppressor ZBTB7A by KDM4 inhibition in human acute myeloid leukemia | Science Translational Medicine
CRISPR screens identify ZBTB7A as a tumor suppressor gene, and therapeutic targeting of KDM4 restores its expression to promote AML differentiation.
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Fat shaming doesn't improve human health, it harms it, researchers find
Adolescence is a period defined by rapid physical, emotional, and social change, and for many young people, it is also shaped by body image issues and weight stigma. Those experiences, researchers say, can drive chronic stress with long-term…
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Pittsburgh nurses are fighting for better staffing ratios — and the research backs them up
Since nursing contract negotiations heated up in January 2026 at UPMC Magee-Womens Hospital in Pittsburgh and at UPMC Altoona, the debate shifted from standard wage disputes to a more fundamental question of patient safety: the…
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Scientists discover hidden sugar layer behind psoriasis
Scientists have uncovered new details about how certain sugars help immune cells enter the skin during psoriasis, a chronic inflammatory disease. These sugars, known as glycans, appear to play a more active role in guiding immune cells than…
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Night Owls Could Be Putting Their Heart Health at Risk
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Are you a night owl or an early bird?
If it’s the former, then…
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Opioids aren't effective for many acute pain conditions, researchers warn
A large review of opioid pain relievers prescribed for acute pain has found these medicines provide only small, short-term relief for some acute conditions and are ineffective for some others. The study set out to review the efficacy and harms of…
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New brain stimulation approach could treat depression in just 5 days
For many people living with depression, standard antidepressant medications do not bring enough relief. In those cases, transcranial magnetic stimulation (TMS) has become an important alternative. This noninvasive therapy uses magnetic pulses to…
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Keto diet may restore exercise benefits in people with high blood sugar
To be healthy, conventional wisdom tells us to exercise and limit fatty foods. Exercise helps us lose weight and build muscle. It makes our hearts stronger and boosts how we take in and use oxygen for energy—one of the strongest predictors of…
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6 in 10 US women projected to have at least one type of cardiovascular disease by 2050
Driven by rising rates in high blood pressure, nearly 6 in 10 women in the U.S. will have some type of cardiovascular disease (CVD) in the next 25 years, according to a new scientific statement published today in Circulation. The work, titled…
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