Circulating tumor DNA, or ctDNA, can predict metastatic risk in patients who receive bladder-sparing treatment for muscle-invasive bladder cancer, but it is not a good predictor of local recurrence within the bladder, according to…
Category: 8. Health
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Study compiles 30 years of adhesion GPCR modulators and their key concentrations
Adhesion GPCRs are a large class of surface proteins that recognize chemical and mechanical stimuli in the body. The rapidly expanding body of knowledge on the therapeutic targeting of these receptors is raising hopes for clinical application in…
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Tick-derived protein discovery can advance treatment for inflammatory diseases
When the immune system detects a harmful or foreign agent it triggers an inflammatory response small proteins called chemokines direct immune cells to the site of the injury or infection, resulting in the invader being…
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Male sex, older age predict poor outcomes in seniors with HFmrEF/HFpEF
Considerable sex disparities are reported in elderly patients with heart failure with mildly reduced or preserved ejection fraction (HFmrEF/HFpEF), with male sex and older age predicting poor outcomes, according to a study published online Jan. 8…
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A randomised controlled trial of a lived experience and education-based weight bias intervention for Australian healthcare students
Jayawickrama RS, O’Connor M, Flint SW, Hemmingsson E, Lawrence BJ. Explicit and implicit weight bias among health care students: a cross-sectional study of 39 Australian universities. EClinicalMedicine. 2023;58:101894.
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Ergothioneine promotes osteogenesis and angiogenesis through PI3K/AKT pathway and prevents glucocorticoid-induced osteonecrosis of the femoral head
Zhang, J., Cao, J., Liu, Y. & Zhao, H. Advances in the pathogenesis of steroid-associated osteonecrosis of the femoral head. Biomolecules 14. https://doi.org/10.3390/biom14060667 (2024).
Kong, N. et al. An injectable self-adaptive polymer as a…
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Immunophenotypic skewing of B cells toward IgD⁻CD27⁻IgG⁺ subtype and metabolic attenuation in colorectal cancer
Roshandel, G., Ghasemi-Kebria, F. & Malekzadeh, R. Colorectal cancer: Epidemiology, risk factors, and prevention. Cancers 16, 1530 (2024).
Hu, T., Li, Z., Gao, C.-Y. & Cho, C. H. Mechanisms of…
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Whole exome sequencing and 12-SNP LDL polygenic score in South Indian patients with familial hypercholesterolemia
World Health Organization. Cardiovascular diseases. World Health Organization. (2021). Available at: https://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds).
Yusuf, S. et al. Global burden of cardiovascular diseases. Part…
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Perioperative enfortumab vedotin + pembrolizumab tied to improved outcomes with bladder cancer
Perioperative enfortumab vedotin plus pembrolizumab and surgery lead to significantly better outcomes among patients with muscle-invasive bladder cancer who are ineligible for cisplatin-based chemotherapy compared with surgery alone, according to…
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Early Exposure to Junk Food Has Brain-Altering Effects
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With the bounty of sugary cereals, sweet snacks, and fast foods available,…
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