Category: Genetics

Problems with a protein known as TAR DNA-binding protein 43 (TDP-43) have long been associated with the neurodegenerative disorders Alzheimer’s disease (AD) and amyotrophic lateral sclerosis (ALS). These…

Our DNA is compacted and arranged into chromosomes, most of which are shaped like X’s. The ends of the chromosomes’ arms are protected with caps known as telomeres. Telomeres are made up of highly repetitive…

Like a toy on a string, the timing of cat domestication has been a moving target. Now researchers have pounced on a new timeline suggesting that tame descendants of African wildcats left the continent more recently than thought.

DNA…

Sometimes, a small error in the sequence of DNA can lead to a very serious disease. Scientists have identified many mutations that arise in a single gene to cause an illness, such as mutations in the CFTR gene…

There is a huge amount of DNA in most human cells, and that DNA has to be carefully compacted and organized so that it will fit into a cell’s nucleus, while the crucial parts of it remain accessible so that…

A new study has provided new insights into the the genetic overlap among some psychiatric disorders, and can help explain why it’s not uncommon for several of these disorders to arise in the same individual….

Purifying proteins efficiently is critical for downstream analysis and assay…

In the 21st century, oncology has achieved extraordinary progress. We can decode a tumor’s genome, tailor therapies to molecular targets, and extend survival through precision treatments. Yet, despite…

Single-cell sequencing is a valuable tool for analyzing complex cellular populations, enabling…

Researchers have used UK Biobank data to reveal more 30 genes that can influence vitamin D levels. While some are previously known for their vitamin D association, others are being identified for the first…