Orthologue identification, phylogenetic analysis and sequence alignment
We used previously identified Cas12a2 protein sequences27 as queries for tBLASTn and BLASTp searches in the NCBI databases (https://www.ncbi.nlm.nih.gov) and the JGI…

We used previously identified Cas12a2 protein sequences27 as queries for tBLASTn and BLASTp searches in the NCBI databases (https://www.ncbi.nlm.nih.gov) and the JGI…

Depienne, C. & Mandel, J.-L. 30 years of repeat expansion disorders: what have we learned and what are the remaining challenges? Am. J. Hum. Genet. 108, 764–785 (2021).
…

Meyer, M. et al. Nuclear DNA sequences from the Middle Pleistocene Sima de los Huesos hominins. Nature 531, 504–507 (2016).
Google Scholar
Duval, M. et al. The…

Deep beneath South Africa’s gold fields, an unexpected gas has been building for billions of years. Helium, essential for MRI scanners and advanced research, sits trapped in the ancient rocks of the Witwatersrand Basin at concentrations rarely…

Astronomers have spotted an unexpectedly hot galaxy cluster in the early universe that’s challenging theories of galactic evolution.
The scorching cluster existed just 1.4 billion years after the Big Bang, blazing far earlier and hotter than…

The upside-down jellyfish Cassiopea andromeda sleeps for roughly 8 hours a day.Credit: Shahar Shabtai/Alamy
Neither jellyfish nor sea anemones have brains. But these animals sleep in ways strikingly similar to humans, according to a study…

January 5, 2026
3 min read
Add Us On GoogleAdd SciAm
Starless ‘Failed Galaxy’ Is First of Its Kind Ever Seen
Scientists have found the best evidence yet for long-predicted “failed galaxies”

The “failed…

To get a better look at brains, Harvard researchers are making microscopes work more like human eyes.
Until recently, the quest to build high-resolution maps of brains — otherwise known as “connectomes” — was stymied by the slow pace…

Advanced alien civilizations may communicate via a series of flashing lights, similar to how fireflies do, a new paper hints. This would potentially make extraterrestrials much harder to spot if we continue to rely on our current observation…

January is peak season for fitness sales, with major discounts on gym memberships, fitness trackers, activewear and beginner-friendly exercise equipment. No wonder — it is a perfect opportunity for retailers to clear inventory and capitalize…