Category: 1. Edi-Choice

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  • A young progenitor for the most common planetary systems in the Galaxy

    A young progenitor for the most common planetary systems in the Galaxy

    Transit observations and analysis

    We analysed a heterogeneous dataset of light curves from space- and ground-based telescopes (Supplementary Table 1) to measure transit times for the ultimate purpose of modelling TTVs. We used PyMC344, exoplanet (

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  • Mimicking opioid analgesia in cortical pain circuits

    Mimicking opioid analgesia in cortical pain circuits

    Sample sizes

    The sample sizes were not statistically determined before the experiments. Rather, the group sizes were on the basis of published literature for the type of manipulation (chemogenetics, site-specific genetic knockout and pharmacology)…

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  • Nutrient requirements of organ-specific metastasis in breast cancer

    Nutrient requirements of organ-specific metastasis in breast cancer

    Mice

    All experiments conducted in this study were approved by the MIT Committee on Animal Care or the MGH Institutional Animal Care and Use Committee. Female B6 and female NSG mice 6–10 weeks of age were used. Animals were housed at ambient…

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  • Ultra-low-density exoplanets observed around a young star

    Ultra-low-density exoplanets observed around a young star

    In 1992, the first planet outside our Solar System was discovered1. Since then, astronomers have catalogued thousands of such exoplanets, most of which are found in planetary systems that are very different to our own. The early stages of a…

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  • Systematic analyses of lipid mobilization by human lipid transfer proteins

    Systematic analyses of lipid mobilization by human lipid transfer proteins

    Lipid transfer proteins (LTPs) maintain the specialized lipid compositions of organellar membranes1,2. In humans, many LTPs are implicated in diseases3, but for the majority, the cargo and auxiliary lipids facilitating transfer remain unknown. We…

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  • A framework for addressing racial and related inequities in conservation

    A framework for addressing racial and related inequities in conservation

  • Western, D., Wright, R. M. & Strum, S. C. (eds). Natural Connections: Perspectives in Community-Based Conservation (Island Press, 1994).

  • Jonas, H., Makagon, J. & Roe, D. in Conservation standards: From Rights to Responsibilities (International…

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  • Mitochondrial transfer from glia to neurons protects against peripheral neuropathy

    Mitochondrial transfer from glia to neurons protects against peripheral neuropathy

    Animals

    Transgenic male and female mice (8 to 12 weeks of age) were used for behavioural and biochemical experiments. Trpv1-Cre mice (JAX: 017769), Aldh1l1creERT2 mice (JAX: 031008), Advillin-Cre mice (JAX: 032536), Cx3cr1creERT2 mice (JAX:…

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  • Blood protein thwarts deadly fungal disease

    Blood protein thwarts deadly fungal disease

    Nature, Published online: 07 January 2026; doi:10.1038/d41586-025-03985-7

    Low levels of albumin, a protein found in blood, are associated with poor clinical outcomes for people with the fungal disease mucormycosis.

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  • Stress controls heterochromatin inheritance via histone H3 ubiquitylation

    Stress controls heterochromatin inheritance via histone H3 ubiquitylation

    Strains and media

    Standard methods were used for the culture, sporulation, genetic crossing and manipulation of S. pombe. Strains were generated through transformations or genetic crosses followed by tetrad dissection. Strains used in this study…

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