Lipid transfer proteins (LTPs) maintain the specialized lipid compositions of organellar membranes1,2. In humans, many LTPs are implicated in diseases3, but for the majority, the cargo and auxiliary lipids facilitating transfer remain unknown. We…
Category: 1. Edi-Choice
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A framework for addressing racial and related inequities in conservation
Western, D., Wright, R. M. & Strum, S. C. (eds). Natural Connections: Perspectives in Community-Based Conservation (Island Press, 1994).
Jonas, H., Makagon, J. & Roe, D. in Conservation standards: From Rights to Responsibilities (International…
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Mitochondrial transfer from glia to neurons protects against peripheral neuropathy
Animals
Transgenic male and female mice (8 to 12 weeks of age) were used for behavioural and biochemical experiments. Trpv1-Cre mice (JAX: 017769), Aldh1l1–creERT2 mice (JAX: 031008), Advillin-Cre mice (JAX: 032536), Cx3cr1–creERT2 mice (JAX:…
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Blood protein thwarts deadly fungal disease
Nature, Published online: 07 January 2026; doi:10.1038/d41586-025-03985-7
Low levels of albumin, a protein found in blood, are associated with poor clinical outcomes for people with the fungal disease mucormycosis.
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Stress controls heterochromatin inheritance via histone H3 ubiquitylation
Strains and media
Standard methods were used for the culture, sporulation, genetic crossing and manipulation of S. pombe. Strains were generated through transformations or genetic crosses followed by tetrad dissection. Strains used in this study…
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An expanded registry of candidate cis-regulatory elements
The registry of cCREs
Anchoring cCREs
We anchored cCREs on two classes of elements: rDHSs and representative transcription factor clusters (TF rClusters). To annotate rDHSs, we refined and filtered DNase hypersensitivity site calls across…
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Albumin orchestrates a natural host defence mechanism against mucormycosis
Microorganisms and culture conditions
R. delemar (99-880)9, R. arrhizus (557969)48 and Cunninghamella bertholletiae (506313)48 have been previously described. Mucor circinelloides (JMRC:NRZ:0774), Rhizomucor pusillus (JMRC:NRZ:0496), Rhizopus…
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Neuro-epithelial circuits promote sensory convergence and intestinal immunity
Gieseck, R. L. 3rd, Wilson, M. S. & Wynn, T. A. Type 2 immunity in tissue repair and fibrosis. Nat. Rev. Immunol. 18, 62–76 (2018).
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Hammad, H., Debeuf, N.,…
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High-voltage anode-free sodium–sulfur batteries | Nature
Liu, R. et al. Establishing reaction networks in the 16-electron sulfur reduction reaction. Nature 626, 98–104 (2024).
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Pan, H. et al….
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Electrochemical defluorinative Matteson-type homologation | Nature
The Matteson homologation, first developed in 1980, elongates carbon chains by insertion into a C−B bond.1 This versatile reaction traditionally requires three steps: carbanion formation, nucleophilic addition to organoboron, and a thermo- or…
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