Category: 1. Edi-Choice

Sample preparation, imaging and rejection criteria

The zircons in this study came from JH samples of Jack Hills metaconglomerate from the Discovery Outcrop on Eranondoo Hill¹, from outcrops up to 900 m to the east, and from one cross-bedded…

• RESEARCH BRIEFINGS
• 04 February 2026

Participants

In this study, we used 11 independent datasets comprising 863 total participants after quality control. These datasets include (1) PIPD dataset⁹⁹: 166 patients with PD and 60 HC individuals; (2) DBS-fMRI dataset: 14 patients with PD,…

Overview of hifiasm (ONT)

The existing hifiasm assembly toolkit consists of three approaches: the original hifiasm⁶, hifiasm (Hi-C)⁸ and hifiasm (UL)¹, each designed for specific purposes. These methods are proposed, respectively, for trio-binning…

Tissue sample collection, preservation and processing

Back skin samples from age-matched adults and one litter of neonatal naked mole rats (Heterocephalus glaber) were maintained at the University of Texas Health Science Center at San Antonio for…

Cell lines and culture methods

All cell lines were cultured in a humidified incubator under normoxia at 37 °C with 5% CO₂. Cell lines were validated by STR analysis and were routinely screened and tested negative for mycoplasma.

Mouse cell…

UKB resource

The protocols for the UKB are overseen by the UKB Ethics Advisory Committee; for more information, see https://www.ukbiobank.ac.uk/ethics and https://www.ukbiobank.ac.uk/wp-content/uploads/2025/01/Ethics-and-governance-framework.pdf….