Category: 1. Edi-Choice

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  • AI succeeds in diagnosing rare diseases

    AI succeeds in diagnosing rare diseases

    Nature, Published online: 18 February 2026; doi:10.1038/d41586-026-00290-9

    An artificial-intelligence system uses clinical data, genetic information and literature searches to suggest diagnoses and provides the underlying reasoning.

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  • This giant virus hijacks cells’ protein-making machinery to multiply wildly

    This giant virus hijacks cells’ protein-making machinery to multiply wildly

    Acanthamoeba polyphaga mimivirus (artist’s impression) is a giant among viruses, both in physical size and because of the size of its genome. Credit: Nanoclustering/Science Photo Library

    Scientists report that a type of giant virus multiplies…

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  • Gene editing treats a mouse model of a neurodevelopmental disorder

    Gene editing treats a mouse model of a neurodevelopmental disorder

  • Yang, K. et al. Nature https://doi.org/10.1038/s41586-026-10113-6 (2026).

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  • Alendar, A. & Berns, A. Gene Dev. 35, 1403–1430 (2021).

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  • Ancestry and somatic profile indicate acral melanoma origin and prognosis

    Ancestry and somatic profile indicate acral melanoma origin and prognosis

    A flowchart describing the analyses, steps and number of samples used in each individual section can be found in Supplementary Fig. 5.

    Patient recruitment and sample collection

    The protocol for sample collection was approved by the Mexican National…

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  • Giant energy storage and dielectric performance in all-polymer nanocomposites

    Giant energy storage and dielectric performance in all-polymer nanocomposites

  • Chu, B. et al. A dielectric polymer with high electric energy density and fast discharge speed. Science 313, 334–336 (2006).

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  • Li, Q. et al….

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  • Integrase anchors viral RNA to the HIV-1 capsid interior

    Integrase anchors viral RNA to the HIV-1 capsid interior

    Recombinant proteins

    The vector pCPH6P-HIV1-IN used for bacterial expression of HIV-1 IN with a cleavable hexahistidine (His6) tag was previously described45. To obtain pCPH6P-SIVtal-IN, the DNA region encoding HIV-1 IN was replaced with a…

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  • Reduced cyclin D3 expression in erythroid cells protects against malaria

    Reduced cyclin D3 expression in erythroid cells protects against malaria

    Cell lines and primary cell cultures

    All cells were cultured under 5% CO2 at 37 °C. HEK-293T and COS7 cells (ATCC) were cultured in Dulbecco’s modified Eagle’s medium (DMEM) with 10% heat-inactivated fetal bovine serum (FBS) (Gibco), 1%

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  • Highly dynamic dural sinuses support meningeal immunity

    Highly dynamic dural sinuses support meningeal immunity

  • Coles, J. A., Myburgh, E., Brewer, J. M. & McMenamin, P. G. Where are we? The anatomy of the murine cortical meninges revisited for intravital imaging, immunology, and clearance of waste from the brain. Prog. Neurobiol. 156, 107–148 (2017).

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  • A Hidden World for 49 Million Years

    A Hidden World for 49 Million Years

    Deep within the caves of New Mexico, researchers have uncovered a mysterious phenomenon that could change how scientists search for life beyond Earth. In 2018, a team of scientists, led by Hazel Barton from the University of Alabama and Lars…

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