Category: 1. Edi-Choice

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  • Malaria is hindered by repression of a cell-cycle protein

    Malaria is hindered by repression of a cell-cycle protein

    Nature, Published online: 18 February 2026; doi:10.1038/d41586-026-00289-2

    A genetic variant that quashes cyclin D3 expression might have been selected for in a population on an island where malaria was once endemic.

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  • Single-cell and isoform-specific translational profiling of the mouse brain

    Single-cell and isoform-specific translational profiling of the mouse brain

    Molecular cloning and AAV production

    The original Ribo-STAMP construct consisted of a Tet-On hRPS2–APOBEC lentiviral expression vector, with a human phosphoglycerate kinase (PGK) promoter driving the expression of rtTA and pac, designed for…

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  • Why China and Europe should collaborate to ‘defossilize’ the world’s carbon

    Why China and Europe should collaborate to ‘defossilize’ the world’s carbon

    Europe and China do not need to compete on the development of defossilization technologies.Credit: Florian Gaertner/Photothek/Getty

    Last month, we described some of the nascent steps a number of…

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  • Chip-scale device efficiently boosts light signals

    Chip-scale device efficiently boosts light signals

    • RESEARCH BRIEFINGS

    Optical-amplifier devices that boost light signals…

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  • Individualized mRNA vaccines evoke durable T cell immunity in adjuvant TNBC

    Individualized mRNA vaccines evoke durable T cell immunity in adjuvant TNBC

    Trial design and data reporting

    The primary objective of this open-label, first-in-human, phase 1, three-arm umbrella trial (ClinicalTrials.gov: NCT02316457) was to separately assess the feasibility, safety, and tolerability profile of two…

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  • An agentic system for rare disease diagnosis with traceable reasoning

    An agentic system for rare disease diagnosis with traceable reasoning

    We introduce DeepRare—an agentic framework designed to support rare disease diagnosis, structured upon a modular, multi-tiered architecture. The system comprises three core components: (1) a central host agent, equipped with a memory bank that…

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  • What we know about autism and ageing — and what we don’t

    What we know about autism and ageing — and what we don’t

    You have full access to this article via your institution.

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  • Roles of microtubules and LIS1 in dynein transport machinery assembly

    Roles of microtubules and LIS1 in dynein transport machinery assembly

  • McKenney, R. J., Huynh, W., Tanenbaum, M. E., Bhabha, G. & Vale, R. D. Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes. Science 345, 337–341 (2014).

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  • Antarctica’s ‘Gravity Hole’ Has Been Quietly Growing Stronger

    Antarctica’s ‘Gravity Hole’ Has Been Quietly Growing Stronger

    For a long time, scientists knew of a “gravity hole” beneath Antarctica—an area with particularly weak gravitational force. Considering the various threats currently faced by the region, scientists are hoping to understand…

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