Ethics statement
Leukopaks from deidentified healthy donors with Institutional Review Board-approved consent forms and protocols were purchased from StemCell Technologies (200-0092). Residuals from leukoreduction chambers after Trima Apheresis…

Leukopaks from deidentified healthy donors with Institutional Review Board-approved consent forms and protocols were purchased from StemCell Technologies (200-0092). Residuals from leukoreduction chambers after Trima Apheresis…

All experiments involving animals were approved by the Yale University Institutional Animal Care and Use Committee and conducted in compliance with all relevant university, state and federal guidelines. The day of vaginal plug detection was…

SiO2 accounts for up to 60% of the Earth’s crust, primarily in minerals such as olivine and pyroxene1. Extraterrestrial bodies, including the Moon2, rocky planets3, chondrules and asteroids2, are derived from SiO2 and other oxides (Al2O3, MgO…

Repeated blows to the head over years of contact sports can lead to chronic brain damage.Credit: Blake Little/Getty
For decades, scientists have struggled to understand exactly how years of taking hits to the head while playing sports can…

Morimoto, R. et al. Open Biol. 11, 200383 (2021).
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Golzari-Sorkheh, M., Yoganathan, K., Chen, E. L. Y., Singh, J. & Zúñiga-Pflücker, J. C. in Thymus Transcriptome…

All cloning was performed in E. coli Trans1-T1 chemically competent cells (TransGen Biotech). Genetic circuit validation used E. coli DH10B (TSC-C09, Tsingke). Cultures were grown in lysogeny broth (LB) at…

When a virus infects a bacterial cell, the viral genome…

Nature, Published online: 18 March 2026; doi:10.1038/d41586-026-00636-3
Antarctic ice cores hint that changes in the ocean might have played a larger part than have greenhouse gases in key climate shifts of the past three million years.

Cloning was performed either by Gibson assembly with the NEBuilder HiFi DNA Assembly Master Mix (New England Biolabs (NEB), E2621) or by site-directed mutagenesis by direct PCR with the KAPA HiFi HotStart Ready Mix (Roche, 07958935001) or…

In this study we provide evidence for the clinical relevance of thymic health in immuno-oncology. We found that high thymic health was consistently associated with improved outcomes across a real-world cohort of 3,476 patients with various cancer…