Category: 1. Edi-Choice

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  • Synthetic circuits for cell ratio control

    Synthetic circuits for cell ratio control

    Bacterial strains and culture conditions

    All cloning was performed in E. coli Trans1-T1 chemically competent cells (TransGen Biotech). Genetic circuit validation used E. coli DH10B (TSC-C09, Tsingke). Cultures were grown in lysogeny broth (LB) at…

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  • An enzyme inside the bacterial-cell membrane chops up viral DNA on entry

    An enzyme inside the bacterial-cell membrane chops up viral DNA on entry

    • RESEARCH BRIEFINGS

    When a virus infects a bacterial cell, the viral genome…

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  • Climate snapshots trapped in ancient ice tell a surprising story

    Climate snapshots trapped in ancient ice tell a surprising story

    Nature, Published online: 18 March 2026; doi:10.1038/d41586-026-00636-3

    Antarctic ice cores hint that changes in the ocean might have played a larger part than have greenhouse gases in key climate shifts of the past three million years.

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  • The E3 ubiquitin ligase mechanism specifying targeted microRNA degradation

    The E3 ubiquitin ligase mechanism specifying targeted microRNA degradation

    Plasmids

    Cloning was performed either by Gibson assembly with the NEBuilder HiFi DNA Assembly Master Mix (New England Biolabs (NEB), E2621) or by site-directed mutagenesis by direct PCR with the KAPA HiFi HotStart Ready Mix (Roche, 07958935001) or…

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  • Thymic health and immunotherapy outcomes in patients with cancer

    Thymic health and immunotherapy outcomes in patients with cancer

    In this study we provide evidence for the clinical relevance of thymic health in immuno-oncology. We found that high thymic health was consistently associated with improved outcomes across a real-world cohort of 3,476 patients with various cancer…

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