Target structures
At the time this study was conducted, there was no experimentally determined structure of TMPRSS2 and we use models of the catalytic domain from ref. 26 instead. Specifically, we exploit a homology model based on…
At the time this study was conducted, there was no experimentally determined structure of TMPRSS2 and we use models of the catalytic domain from ref. 26 instead. Specifically, we exploit a homology model based on…
The epigenetic histone H3 Lys4 methylation (H3K4me) mark is usually linked to transcriptional activation, whereas the histone H3 Lys27 methylation (H3K27me) mark signals repression. These marks are found together on the promoters of…
A total of 103 participants aged 18 to 35 years (M = 26.8, SD = 3.8) successfully completed at least one out of three neurostimulation sessions. Two participants could not complete any session due to failed…
The materials used in this study unless otherwise stated, were purchased from Sigma Aldrich (MA, USA) and Thermo Scientific (MA, USA).
The amino acid sequence of PfGrp170 with PlasmoDB accession number…
New fossil evidence suggests the Cambrian explosion—long hailed as the dramatic birth of complex animal life—may not have been the sudden evolutionary event we thought. Researchers analyzing ancient trace fossils from 545 million years ago…
Researchers at the University of Tokyo explored how female body odor can influence behaviors in men. They found certain scent compounds in female body odor increased during ovulation and can subtly influence how men feel. When these…
Apart from carrying the information to encode proteins in, RNA molecules can adopt intricate 2D and 3D structures. Specifically, the same RNA molecule can switch between ON and OFF structures, modulating the ability of ribosomes to…
Researchers at the University of Southampton have worked out how bacteria defend themselves against viruses called phages and the new insights could be key to tackling antibiotic resistance.
Phages are seen as a promising…
In the same vein as weather forecast models that predict developing storms, researchers now have developed a method to predict the cell activity in tissues over time. The new software combines genomics technologies with…
A new research paper was published in Aging (Aging-US) Volume 17, Issue 6, on June 13, 2025, titled “Development of a novel transcriptomic measure of aging: Transcriptomic Mortality-risk Age (TraMA).”
In this study, led by Eric…