The epigenetic histone H3 Lys4 methylation (H3K4me) mark is usually linked to transcriptional activation, whereas the histone H3 Lys27 methylation (H3K27me) mark signals repression. These marks are found together on the promoters of…
Category: 5. Biology
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Personalized home based neurostimulation via AI optimization augments sustained attention
Experiment 1’s participants
A total of 103 participants aged 18 to 35 years (M = 26.8, SD = 3.8) successfully completed at least one out of three neurostimulation sessions. Two participants could not complete any session due to failed…
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Biochemical and biophysical characterization of Plasmodium falciparum glucose regulated protein 170
Materials
The materials used in this study unless otherwise stated, were purchased from Sigma Aldrich (MA, USA) and Thermo Scientific (MA, USA).
PfGrp170 plasmid construct design
The amino acid sequence of PfGrp170 with PlasmoDB accession number…
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Endoplasmic reticulum-mitochondria coupling prompts ZBP1-mediated RPE cell PANoptosis in age-related macular degeneration
Materials and reagents
Sodium iodate (NaIO3) was bought from Sigma-Aldrich (St. Louis, USA). Various compounds and reagents were bought from different suppliers: BAPTA-AM, Chloroquine (CQ), OSMI-1, Dideoxycytidine (ddC), Cyclosporin A (CsA),…
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The brain fires up immune cells when sick people are nearby
Brain areas that help to monitor the envelope of space close to a person help to fire up immune cells when infection threatens. Credit: Zephyr/Science Photo Library
The brain activates front-line immune cells in response to the mere sight of a…
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Nondestructive freshness recognition of chicken breast meat based on deep learning
Preparation and recognition process of chicken breast freshness
The broiler chickens used in this study were sourced from Tiancheng Farm in Xuancheng City, Anhui Province. The specific process for the preparation and recognition of chicken breast…
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c-Kit signaling confers damage-resistance to sweet taste cells upon nerve injury
Mice
All animal procedures were approved by the Institutional Animal Care and Use Committee of Korea University (KOREA-2022-0142). Mice were housed in a temperature-controlled environment (22 °C) under a 12-h light-dark cycle with ad libitum…
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The value of acetylation reader YEATS2 in hepatocellular carcinoma management
Screening of acetylation-related genes
We obtained 240 acetylation-related genes from the Molecular Signatures Database (MSigDB) (https://www.gsea-msigdb.org/gsea/msigdb/, accessed March 19, 2024)12 (Supplementary TableS1). For 377 HCC patients…
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Restoring balanced HSC youth | Nature Immunology
Hematopoietic stem cells (HSCs) in aged individuals become less functional in their regenerative potential and biased towards myeloid cell output with reduced lymphoid and erythroid cell production. In Nature Aging, Sun et al. investigate the…
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The influence of physical activity on the mental health of high school students: the chain mediating effects of social support and self-esteem
Lee, J., Goh, M. & Yeo, S. Mental health awareness of secondary schools students: Mediating roles of knowledge on mental health, knowledge on professional help, and attitude towards mental health. Heliyon.
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