Target structures
At the time this study was conducted, there was no experimentally determined structure of TMPRSS2 and we use models of the catalytic domain from ref. 26 instead. Specifically, we exploit a homology model based on…
At the time this study was conducted, there was no experimentally determined structure of TMPRSS2 and we use models of the catalytic domain from ref. 26 instead. Specifically, we exploit a homology model based on…
The epigenetic histone H3 Lys4 methylation (H3K4me) mark is usually linked to transcriptional activation, whereas the histone H3 Lys27 methylation (H3K27me) mark signals repression. These marks are found together on the promoters of…
A total of 103 participants aged 18 to 35 years (M = 26.8, SD = 3.8) successfully completed at least one out of three neurostimulation sessions. Two participants could not complete any session due to failed…
The materials used in this study unless otherwise stated, were purchased from Sigma Aldrich (MA, USA) and Thermo Scientific (MA, USA).
The amino acid sequence of PfGrp170 with PlasmoDB accession number…
Sodium iodate (NaIO3) was bought from Sigma-Aldrich (St. Louis, USA). Various compounds and reagents were bought from different suppliers: BAPTA-AM, Chloroquine (CQ), OSMI-1, Dideoxycytidine (ddC), Cyclosporin A (CsA),…
Brain areas that help to monitor the envelope of space close to a person help to fire up immune cells when infection threatens. Credit: Zephyr/Science Photo Library
The brain activates front-line immune cells in response to the mere sight of a…
The broiler chickens used in this study were sourced from Tiancheng Farm in Xuancheng City, Anhui Province. The specific process for the preparation and recognition of chicken breast…
All animal procedures were approved by the Institutional Animal Care and Use Committee of Korea University (KOREA-2022-0142). Mice were housed in a temperature-controlled environment (22 °C) under a 12-h light-dark cycle with ad libitum…
We obtained 240 acetylation-related genes from the Molecular Signatures Database (MSigDB) (https://www.gsea-msigdb.org/gsea/msigdb/, accessed March 19, 2024)12 (Supplementary TableS1). For 377 HCC patients…
Hematopoietic stem cells (HSCs) in aged individuals become less functional in their regenerative potential and biased towards myeloid cell output with reduced lymphoid and erythroid cell production. In Nature Aging, Sun et al. investigate the…