Category: 5. Biology

Ongoing memory storage in a network model with biologically constrained synapses leads to the partial overwriting of previously encoded patterns, Fig. 1. When such a network is driven by external input, the resulting patterns of activity will…

The values of tau are generally low in all super-populations

We analysed individuals from 5 super-populations, including 656 Africans (AFR); 347 Admixed Americans (AMR); 503 East Asians (EAS); 498 Europeans (EUR); and 486 South Asians (SAS)…

Participants

This study included 8 semiprofessional male baseball pitchers (6 right-handed, 2 left-handed) from a company baseball league in Japan. The participants had a mean (± standard deviation) age of 28.6 ± 5.1 years, height of…

USP1/UAF1 prefers to cleave K63- and K48-PCNA-Ub_N using exo-cleavage

To study the cleavage mechanism of USP1/UAF1, we produced a variety of defined K63- or K48-ubiquitinated PCNA substrates (Fig. 1). We used different combinations of wildtype…

Study 1

Sample characteristics

The first sample was assessed in the framework of an educational intervention study in primary schools²⁷. The data analyzed in this paper were not part of the regular data collection of this intervention study but a…

mCA plasmid generation

The bicistronic dual-reporter lentiviral construct was generated using the NEBuilder HIFI DNA Assembly Cloning Kit (#E5520S, New England Biolabs) with the lentiviral vector pRRL-EF1a-WPRE³⁰ as backbone, linearized with the…

Experiments with yeast not related to fluorescence microscopy

Yeast culture conditions and metabolic labelling

Yeast cells were cultured at 30 °C and 160 r.p.m. in synthetic complete medium (pH 6.0) containing 0.17% yeast nitrogen base…