Category: 5. Biology

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  • Condensate-mediated intracellular organelle sequestration | Nature Reviews Molecular Cell Biology

    Condensate-mediated intracellular organelle sequestration | Nature Reviews Molecular Cell Biology

    Compartmentalization is essential for the correct function of eukaryotic cells, and many biomolecules and biochemical events are localized in organelles, which are in a dynamic flux of material or information with other cellular compartments….

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  • Applications of multiplexed CRISPR–Cas for genome engineering

    Applications of multiplexed CRISPR–Cas for genome engineering

  • Capecchi, M. R. Gene targeting in mice: functional analysis of the mammalian genome for the twenty-first century. Nat. Rev. Genet. 6, 507–512 (2005).

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  • Rouet, P., Smih,…

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  • HIV-1 capsid found guilty of breaking and entering

    HIV-1 capsid found guilty of breaking and entering

    HIV-1 capsid found guilty of breaking and entering

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  • PRMT1-mediated methylation of UBE2m promoting calcium oxalate crystal-induced kidney injury by inhibiting fatty acid metabolism

    PRMT1-mediated methylation of UBE2m promoting calcium oxalate crystal-induced kidney injury by inhibiting fatty acid metabolism

    Human samples study

    Samples were obtained from eight patients with nonfunctioning kidneys due to KS undergoing nephrectomy at Renmin Hospital of Wuhan University (mean age 49.1 ± 8.0 years; five males and three females) (Table S1). The stones…

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  • Interactive effects of ocean acidification and warming disrupt calcification and microbiome composition in bryozoans

    Interactive effects of ocean acidification and warming disrupt calcification and microbiome composition in bryozoans

  • Sage, R. F. Global change biology: a primer. Glob. Change Biol. 26, 3–30 (2020).

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  • Carbonne, C. et al. Two temperate corals are tolerant to low pH regardless of previous exposure to natural CO2

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  • Author Correction: The long-term effects of chemotherapy on normal blood cells

  • These authors contributed equally: Emily Mitchell, My H. Pham, Anna Clay, Jyoti Nangalia, Michael R. Stratton.

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  • Short-term responses of ground-dwelling arthropod communities to habitat loss and fragmentation in experimental mesoscale landscapes

    Short-term responses of ground-dwelling arthropod communities to habitat loss and fragmentation in experimental mesoscale landscapes

  • Fahrig, L. et al. Is habitat fragmentation bad for biodiversity? Biol. Conserv. 230, 179–186 (2019).

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  • Fletcher, R. J. et al. Is habitat fragmentation good for biodiversity? Biol. Conserv. 226,…

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  • CPADS enables comprehensive analysis of drug resistance across 44 cancer types

    CPADS enables comprehensive analysis of drug resistance across 44 cancer types

    CPADS integrates data from the Gene Expression Omnibus (GEO), The Cancer Genome Atlas (TCGA), and the Genomics of Drug Sensitivity in Cancer (GDSC) databases, encompassing over 29,000 samples across 44 cancer types and involving 288…

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  • The Loch Ness Monster’s body is a ‘zoological impossibility’

    The Loch Ness Monster’s body is a ‘zoological impossibility’

    The earliest accounts of a mysterious creature lurking in Loch Ness date back…

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