Category: 5. Biology

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  • An escort to the ER

    An escort to the ER

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  • Uncaged by ROS | Nature Chemical Biology

    Reactive oxygen species (ROS) are both byproducts of cellular metabolism and essential signaling molecules, but they need to be carefully regulated as high ROS levels can cause oxidative damage to biomolecules. Bioorthogonal probes activated by…

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  • Mitochondria defend the nuclear envelope

    The nuclear envelope (NE) is a double-layer membrane structure that surrounds the nucleus in eukaryotic cells. A previous screening study showed that knocking down genes related to mitochondrial function can lead to abnormal nuclear morphology….

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  • Adipogenic transdifferentiation reprograms EMT-high PDAC cells into a post-mitotic adipocyte-like state and limits metastasis

    Adipogenic transdifferentiation reprograms EMT-high PDAC cells into a post-mitotic adipocyte-like state and limits metastasis

  • Siegel RL, Kratzer TB, Giaquinto AN, Sung H, Jemal A. Cancer statistics, 2025. CA Cancer J Clin. 2025;75:10–45.

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  • Dreyer SB, Beer P, Hingorani SR, Biankin AV. Improving outcomes of patients with…

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  • Network model for alignment, stitching and slice-to-volume 3D reconstruction of large-scale spatially resolved slices

  • Marx, V. Method of the year: spatially resolved transcriptomics. Nat. Methods 18, 9–14 (2021).

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  • Ståhl, P. L. et al. Visualization and analysis of gene expression in tissue sections by spatial…

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  • Paternal heat conditioning enhances offspring’s thermal resilience via epigenetic regulation of mir-210a

  • Capucchio, M. T. et al. The Disturbed Habitat and Its Effects on the Animal Population (Anim Behav. Intech open, 2019).

  • Zaccaria, E., van der Valk, E., Kar, S. K., Rebel, J. M. J. & Schokker, D. Mini review: studying epigenomic alterations can…

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  • Cysteine-reactive mitigators of small vessel disease-related NOTCH3 mutants

  • Wang, M. M. Cadasil. Handb. Clin. Neurol. 148, 733–743. https://doi.org/10.1016/B978-0-444-64076-5.00047-8 (2018).

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  • Chabriat, H., Joutel, A., Dichgans, M., Tournier-Lasserve, E. & Bousser, M….

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  • How birds are spreading plastic pollution

    How birds are spreading plastic pollution

    Hungry gulls do not only steal our chips and sandwiches. They learn our habits, and look for reliable sources of food. That includes waste treatment centers, landfill or anywhere food waste is concentrated. Many gull populations have moved inland…

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  • Magnetic fields guide lab-grown blood vessels into precise patterns for drug testing

    Magnetic fields guide lab-grown blood vessels into precise patterns for drug testing

    Animal studies often fail to predict human tissue responses to new drugs or newly developed therapies. Besides generating tremendous costs for clinical studies, it also raises significant ethical concerns. Therefore, novel approaches to mimicking…

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