Santos Correa, S., Schultz, J., Lauersen, K. J. & Soares Rosado, A. Natural carbon fixation and advances in synthetic engineering for redesigning and creating new fixation pathways. J. Adv. Res. 47, 75–92 (2023).
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Category: 5. Biology
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Regulation of airway fumarate by host and pathogen promotes Staphylococcus aureus pneumonia
All experimental procedures were conducted in accordance with relevant ethical regulations and approved by the appropriate institutional review boards or ethics committees.
Human subjects
All human samples (healthy individuals and CF patients) were…
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Neonicotinoids and Varroa mites force the extending of longevity in a bee colony during overwintering to forget
For details, please refer to Methods S1–S3 in the supplementary materials.
Determination method of apparent longevity (AL) (refer to Supplementary Method S1)
Mathematical model
The following mathematical model1 can estimate AL from the number of…
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Structure of CFTR bound to (R)-BPO-27 unveils a pore-blockage mechanism
Saint-Criq, V. & Gray, M. A. Role of CFTR in epithelial physiology. Cell. Mol. Life Sci. 74, 93–115 (2017).
Google Scholar
Cheng, S. H. et al. Phosphorylation of the R domain by cAMP-dependent…
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The CCL2-CCR2 axis drives neuromuscular denervation in amyotrophic lateral sclerosis
Study design
We conducted the initial quantification of leukocyte and macrophage infiltration in the skeletal muscle of control individuals and ALS patients. We excluded muscle samples from clinically slow-progressing patients. We then assessed…
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Modulation of oral vaccine efficacy by the gut microbiota
Vaccination has eradicated or nearly eradicated smallpox and polio, reduced the severity of many diseases, and can prevent the development of cancers, such as cervical cancer1. Since the beginning of the coronavirus disease 2019 (COVID-19)…
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Pathogenic morphological signatures of perturbations in mitochondrial-related genes revealed by pooled imaging assay
Culture and transfection
Human osteosarcoma U2OS cell line (U2OS, ATCC HTB-96) with doxycycline-inducible Cas913 was cultured in McCoy’s 5 A Modified Medium (16600082, Gibco, Gaithersburg, MD, USA) supplemented with 10% tetracycline-free fetal…
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METTL9 sustains vertebrate neural development primarily via non-catalytic functions
Animals’ use followed recommendations of the European Community (2010/63/UE) and protocol approved by Italian Ministry of Public Health (Auth. #501/2021-PR). Sex determination of the Xenopus embryos used in this study was not conducted due to…
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Canonical Wnt signaling regulates Mbd3 protein stability during neurogenesis
Canonical Wnt signaling promotes Mbd3 protein stability
Our previous study explored the close association between Mbd3 and the neurogenesis potential of NPCs30. In addition, emerging evidence has identified the Wnt signaling pathway as a factor…
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