Heart attacks remain a leading cause of death and disability worldwide. The permanent loss of heart muscle cells-known as cardiomyocytes-and the heart’s limited regenerative capacity often led to chronic heart failure.
Current…
Category: 5. Biology
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Study sheds light on molecular mechanisms of brain aging
Aging and neurodegeneration are both known to disrupt the production of functional proteins in cells – a process called “proteostasis,” or protein homeostasis. Brain cells in particular fall prey to proteostasis disruptions, which…
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The second messenger c-di-AMP controls natural competence via ComFB signaling protein
Natural competence requires a contractile pilus system. Here, we provide evidence that the pilus biogenesis and natural competence in cyanobacteria are regulated by the second messenger c-di-AMP….
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Phosphorylation powers plant Polycomb | Nature Plants
Lewis, P. H. Melanogaster – new mutants: report of Pamela H. Lewis. Dros. Inform. Serv. 21, 69 (1947).
Muller, J. et al. Cell 111, 197–208 (2002).
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Nde1 promotes Lis1 binding to full-length autoinhibited human dynein 1
Reck-Peterson, S. L., Redwine, W. B., Vale, R. D. & Carter, A. P. The cytoplasmic dynein transport machinery and its many cargoes. Nat. Rev. Mol. Cell Biol. 19, 382–398 (2018).
McNally, F. J….
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Presence of high-risk nano particulate matters in powder injection: microscopic evaluation and investigation of particles contamination
The presence of particulate matter in parenteral or injectable medicines remains a significant concern for both manufacturers and consumers. Media outlets frequently report on product recalls due to particle contamination. The most common types…
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Contribution of displacement, duration, and velocity on auditory motion direction perception in macaque monkeys
Psychophysical performance
First, we analyzed psychometric performance for each monkey on the motion direction task to compare their performance across conditions with the same duration, displacement, and velocity as exemplified in Fig. 1C. These…
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Comparative metagenomics on community structure and diversity of rhizomicrobiome associated with monoculture and soybean precedent carrot
Shotgun metagenomics approach was employed in this study to provide insight into how cropping systems affect the diversity and community structure of the core microbiomes associated with the carrot rhizosphere. The study compared the abundance…
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Deep-learning model for embryo selection using time-lapse imaging of matched high-quality embryos
Study design and population
This research was a retrospective observational study carried out of IVF cycles peformed in the reproductive medicine center at Angers hospital (France) between January 2020 and February 2023. We included women from 18…
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BAT mitochondria: whitening meets softening
BAT mitochondria: whitening meets softening
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