Category: 5. Biology

Mice

C57BL/6N mice were purchased from Janvier (Le Genest Saint Isle, France, stock no. C57BL/6NRj). BCMA-KOΔ3 mice were established by crossing the BCMA:Tom reporter mouse¹⁰ with a Transcription Factor E2-Alpha (E2A)-cre deleter line¹⁵. After…

Experimental animals and sampling

The discovery cohort included 129 Yorkshire pigs (female). All sows were raised under standardized conditions on a commercial pig farm in Fujian Province, China. The primary nutrient components of the diets are…

Our goal is to develop and benchmark a method to “coerce” AlphaFold2 to predict multiple conformations of a protein that are consistent with an experimental data set. Therefore, we initially selected two transporters to test the hypothesis…

Using in vitro germination and acetocarmine tests, the germination of fresh pollen from two kiwifruit cultivars was investigated (Table 3). The results of both viability tests varied depending on the cultivar. The in vitro germination test…

Alzheimer’s disease (AD) is the most common form of dementia, thought to affect…

Australian entomologists have described a spectacular new species of the stick insect genus Acrophylla from two female specimens as well as eggs.

First described in 1835,

A team from the Max-Planck-Institut für Kohlenforschung, Hokkaido University, and Osaka University has discovered that subtle differences in molecular structure can have a major impact on the performance of mRNA-based drugs. Their…

Animals that hibernate are incredibly resilient. They can spend months without food or water, muscles refusing to atrophy, body temperature dropping to near freezing as their metabolism and brain activity slow to a crawl. When they…

Fine artist Laura Shape uses quite an unexpected medium in her visual artwork. It…

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in T-cell development…