Category: 5. Biology

For a comprehensive description of the methods, please refer to our previous studies^11,12,13,14. Here, we provide a brief overview of our methods.

Participants

We obtained data from 87 unique participants (38 males, 49 females, aged 21.6 ± 2.2…

The research conducted here complies with all relevant ethical regulations of Genentech Inc.

Epiregulon

The Epiregulon workflow consists of several components: GRN construction, pruning of networks (optional), estimation of weights, calculation of…

Mice and experimental conditions

10-week-old C57BL/6 N mice were used for both 1-day and 1-week TAC/Sham experiments.

The animal experiment protocols were approved under animal license number G-228/18.

TAC/Sham surgical procedure

Mice were…

Inclusion and ethics

All animal experiments were approved by the Institute of Experimental Animal Ethics Committee of Jinan University (Guangzhou, China). The approval ID for the use of animals were 00365755 and 00379905. The human specimens used…

METTL5 is upregulated and is a prognostic value in MM

To explore the potential function of m⁶A “writers” in MM, we analyzed the GSE6477 dataset of MM patients and normal donors (NDs) and found that METTL5 mRNA expression was significantly…

Ethical statement

All research described here complies with all relevant ethical regulations and was approved by the Weill Cornell Medicine Institutional Animal Care and Use Committee (under protocol number 0610-549 A) for mouse studies or by…

CVD and cancer are the leading causes of death in the 21 st century^6,11, and these two diseases have previously caught much attention from cardiovascular specialists and oncologists, respectively. While, with the improvement of anti-cancer…

DNA constructs

DNA was obtained from the following sources: ConMem wt³², C_L ConMem, and EMC1-myc from GeneArt Synthesis, Thermo Fisher; BCAP31, VMA21, TOR1AIP2, SIGMAR1, SLC3A2, TMX4, GPX8, and TMEM38B from Twist Bioscience. EMC1-FLAG was a kind…

Effects of different concentrations of Sacha Inchi leaf extracts on lipid oxidation in beef patties

The study performed evaluation of lipid oxidation by determining both primary and secondary oxidation products in beef patties. This primary…