Category: 5. Biology

Protein constructs

The following cDNA constructs previously described^20,26 were used in this study: full-length VAMP2 (mouse His⁶-SUMO-VAMP2, residues 1-116); full-length SNAP25 (mouse His⁶-SNAP25b, residue 1-206); Synaptotagmin (rat Synaptotagmin…

Annotation and dynamic changes of immune cell subtypes in the CRC TME

To investigate the cellular architecture of the TME in CRC, we analysed publicly available single-cell RNA sequencing (scRNA-seq) data²⁰. Details of the pre-processing workflow…

Uncovering how rare genetic changes disrupt brain signaling and structure, this landmark study sheds new light on the roots of schizophrenia and opens doors for future therapies.

Study: Whole-exome sequencing analysis identifies…

On Norway’s frosty northern coast, a cave sat virtually unknown to humans for…

Two new studies by University of Utah researchers provide clues on how to unlock these hibernating abilities, opening the door to someday developing treatments that could reverse neurodegeneration and diabetes.

In a first-of-its-kind clinical trial, UCLA scientists have shown it’s possible to reprogram a patient’s blood-forming stem cells to generate a continuous supply of functional T cells, the immune system’s most powerful…

It’s tough out there for male spiders. The sexual dimorphism is so extreme in…

Scientists at St. Jude…

A team of Chinese researchers led by Prof. GAO Caixia from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has developed two new genome editing technologies, known collectively as Programmable…