Category: 5. Biology

This phenomenon of “hyperdominance” by a few species has significant…

Each cell has their own genetic code that helps maintain viability and directs function.  This genetic code is commonly referred to as deoxyribonucleic acid or DNA. DNA is the molecule that carries genetic…

The Human Intestinal Bacteria Collection (HiBC) offers scientists access to over 300 live gut bacterial strains, many never studied before, empowering research into inflammation, immunity, and future microbiome-based therapies.

A decades-old challenge in neuroscience has been solved by harnessing artificial intelligence (AI) to identify the electrical signatures of different types of brain cells for the first time, as part of a study in mice led by…

Amino acid scarcity induces the ATF4 pathway in T cells

To harness the ATF4 pathway for enhancing CAR-T-cell functions in the solid tumor microenvironment, we utilized an in vitro model (Fig. 1A) to examine the behavior of activated CD3⁺ T cells…

Data retrieval and data preprocessing for rhyQTL mapping (Step 1 in Fig. 1a)

The genotype data of 838 individuals in GTEx project were downloaded from dbGaP with accession number phs000424.v8.p2. To identify rhyQTLs, we used PLINK⁵², a tool set…

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This is a summary of: Zhao, H. et al. Typhoid toxin causes neuropathology by disrupting the blood–brain…

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This is a summary of: Chai, H. et al. Tri-omic single-cell mapping of the 3D epigenome and transcriptome in…

Definition of the problem

Multi-label classification refers to the model outputting multiple related but independent Gleason grading labels for a single whole slide image (WSI). For example, the model predicts both the primary Gleason pattern and…