Category: 5. Biology

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  • Single-cell and spatial transcriptomics reveals an anti-tumor neutrophil subgroup in microwave thermochemotherapy-treated lip cancer

    Single-cell and spatial transcriptomics reveals an anti-tumor neutrophil subgroup in microwave thermochemotherapy-treated lip cancer

    Single-cell and spatial transcriptomics profiling of LSCC under MTC

    Over the last 5 years, our group has treated 37 LSCC patients with MTC. After the entire treatment, 25 patients had satisfactory therapeutic effects, and 18 had no recurrence…

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  • Reviewing the complexities of bacterial biocide susceptibility and in vitro biocide adaptation methodologies

    Reviewing the complexities of bacterial biocide susceptibility and in vitro biocide adaptation methodologies

  • Hora, P., Pati, S. G., McNamara, P. J. & Arnold, W. A. Increased use of quaternary ammonium compounds during the SARS-CoV-2 pandemic and beyond: Consideration of Environmental Implications. Environ. Sci. Technol. Lett.

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  • Unraveling the black box in neural signal analysis

    Current technologies for recording neural activity generate large amounts of data. These data can be analyzed and decoded with biophysical models or with deep learning-based approaches. While the former is conducive to a detailed understanding of…

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  • Development and validation of a cancer-associated fibroblast gene signature-based model for predicting immunotherapy response in colon cancer

    Development and validation of a cancer-associated fibroblast gene signature-based model for predicting immunotherapy response in colon cancer

  • Sung, H. et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J. Clin. 71 (3), 209–249 (2021).

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  • TRIM23 mediates cGAS-induced autophagy in anti-HSV defense

    TRIM23 mediates cGAS-induced autophagy in anti-HSV defense

    Cells and viruses

    Human embryonic kidney cells (HEK293T, CRL3216; ATCC), ATG5 KO HEK293T cells29, hTERT immortalized human dermal fibroblasts (HDFs, a gift from P. Hearing, Stony Brook University)90, human adenocarcinoma cells (HeLa, CCL-2; ATCC), HeLa…

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  • Fat accumulation in middle-aged male animals

    Fat accumulation in middle-aged male animals

    White adipose tissue (WAT) often accumulates during ageing, especially in the visceral area, and this accumulation is associated with increased risk of metabolic disorders. The mechanisms that drive WAT expansion during early ageing are not fully…

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  • Tracking gene transfer using RNA tools

    Gene transfer has a central role in shaping microbial community, and influences cell–cell interactions, niche adaptation and the spread of antibiotic resistance genes. Accurately tracking gene transfer events across species in real-world…

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