Scientists have been searching for treatments for neurodegenerative disorders like Alzheimer’s and Parkinson’s for many years, yet they remain elusive, even as increasing numbers of people are diagnosed with…
Category: 5. Biology
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The Link Between Biological Age and Dementia
A recent large-scale cohort study leveraging the UK Biobank database provides new evidence that accelerated biological aging (BA) is significantly associated with an increased risk of developing dementia. The…
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New brain network discovery could revolutionize depression diagnosis
In a comprehensive Genomic Press Commentary published today, researchers have identified what could be the first reliable biomarker for depression risk, potentially transforming how this devastating condition is identified and…
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Streamlining High-Throughput Screening with Revvity’s Automated Workflow Solutions
Revvity offers comprehensive solutions designed to help accelerate laboratory workflows, assisting researchers meet targets faster and bring new therapies to market sooner. Our integrated approach combines…
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Hearing Aids May Reduce Loneliness in Elderly
The provision of hearing aids and advice appears to preserve social connections among older adults, ultimately preventing loneliness. The corresponding study was published in JAMA Internal Medicine.
“Our…
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Exploring the role of RNA binding proteins and circular RNAs in cancer
The interaction between RNA-binding proteins (RBPs) and circular RNAs (circRNAs) has emerged as a key area of interest in understanding cancer biology. As critical regulators of gene expression, RBPs control the formation and…
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RANBP2 identified as key regulator in the progression of multiple solid tumors
The nuclear pore complex protein RANBP2 has emerged as a critical factor in the development and progression of various solid malignancies. As a SUMO E3 ligase, RANBP2 plays a pivotal role in post-translational modification,…
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HIV Drugs May Protect Against Alzheimer’s Disease
Drugs used to treat HIV may protect against Alzheimer’s disease (AD). The corresponding study was published in Alzheimer’s & Dementia. The findings provide a rationale for clinical testing.
“It’s…
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Mitochondrial DNA editing offers new hope for neurodegenerative disease treatment
Mitochondrial DNA (mtDNA) editing has emerged as a revolutionary approach in the fight against neurodegenerative diseases (NDDs). As these diseases continue to impose a significant global health burden, the innovative use of…
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ATP functions as a pathogen-associated molecular pattern to activate the E3 ubiquitin ligase RNF213
Protein sequence analysis, cloning of mouse RNF213 expression constructs, expression and purification of mouse RNF213 protein, preparation of fluorescently labeled ubiquitin, the RNF213 SDS-PAGE-based auto-ubiquitination assay, cryo-EM analyses,…
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