Wu, T., Liu, Y., Liu, J., Chen, Z. & Huo, Y.-X. Metabolic engineering and regulation of diol biosynthesis from renewable biomass in Escherichia coli. Biomolecules 12, 715 (2022).
…
Category: 5. Biology
-
Biochemical and hematological reference intervals in rhesus and cynomolgus macaques and implications for vaccine and drug development
Age differences in biochemical and hematological parameters
The objective of this study was to define internal RIs of classical biochemical and hematological parameters in healthy macaques housed at KI and sampled longitudinally. The animals…
Continue Reading
-
Heterogeneity of TP53 mutations necessitates differentiation with p53-rescue therapies
We read with interest the Review by Peuget et al. (Peuget, S., Zhou, X. & Selivanova, G. Translating p53-based therapies for cancer into the clinic. Nat. Rev. Cancer 24, 192–215 (2024))1 that introduces the development of p53-based therapies….
Continue Reading
-
Comparison of RNA- and DNA-based 16S amplicon sequencing to find the optimal approach for the analysis of the uterine microbiome
Stinson, L. F., Boyce, M. C., Payne, M. S. & Keelan, J. A. The Not-so-Sterile womb: evidence that the human fetus is exposed to Bacteria prior to birth. Front. Microbiol. 10, 1124. https://doi.org/10.3389/fmicb.2019.01124 (2019).
Continue Reading
-
Angiogenesis related gene signatures predict prognosis and guide therapeutic strategies in renal clear cell carcinoma
The pathogenesis of KIRC is multifaceted, with various acquired risk factors, such as smoking and obesity, as well as hereditary predispositions contributing to the onset of kidney cancer. Notable genetic alterations associated with KIRC include…
Continue Reading
-
ZSCAN21 mediates the pathogenic transcriptional induction of α-synuclein in cellular and animal models of Parkinson’s disease
Materials
Culture media and TrypLE were from Thermo Fisher Scientific. Recombinant human basic Fibroblast Growth Factor (bFGF, #4114-TC-01M) and Glial cell line-Derived Neurotrophic Factor (GDNF, #202-GD-010) were from R&D systems….
Continue Reading
-
LipidIN: a comprehensive repository for flash platform-independent annotation and reverse lipidomics
Ethical statement
Written informed consent was obtained from each participant or from the participant’s parents or legal guardians in the discovery and validation cohorts, and the study was conducted according to the Declaration of Helsinki….
Continue Reading
-
Adaptability to climate change is difficult to predict
Adaptability to climate change is difficult to predict
Continue Reading
-
Suppression of plastid-to-nucleus gene transfer by DNA double-strand break repair
Kleine, T., Maier, U. G. & Leister, D. DNA transfer from organelles to the nucleus: the idiosyncratic genetics of endosymbiosis. Annu. Rev. Plant Biol. 60, 115–138 (2009).
Google…
Continue Reading
