Science News Daily App

Category: 5. Biology

Continue Reading

  • Prostaglandin endoperoxide synthase 2 regulates neuroinflammation to mediate postoperative cognitive dysfunction in mice

    Prostaglandin endoperoxide synthase 2 regulates neuroinflammation to mediate postoperative cognitive dysfunction in mice

    Animals

    Four-month-old male C57BL/6 mice weighing 26–30 g were used in this study (Chengdu Dossy Experimental Animals Co., LTD, China). In vivo experiments have been ethically approved by the Ethics Committee of Laboratory Animal Care and…

    Continue Reading

  • Large vesicles from ageing neutrophils: novel safeguards for the resolution of inflammation

    Large vesicles from ageing neutrophils: novel safeguards for the resolution of inflammation

    In a recent publication in Cell, Hsu and colleagues describe a novel kind of extracellular vesicle that is involved in the resolution of inflammation.1 Such large ageing neutrophil-derived vesicles…

    Continue Reading

  • Inhibitory effects of high extracellular l-glutamate concentrations on skeletal myogenesis

    Inhibitory effects of high extracellular l-glutamate concentrations on skeletal myogenesis

  • Hindi, S. M., Tajrishi, M. M. & Kumar, A. Signaling mechanisms in mammalian myoblast fusion. Sci. Signal. 6, re2 (2013).

    Article 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Yin, H., Price, F. &…

    • Continue Reading

  • ultra-powerful CRISPR treatment trialled in a person

    ultra-powerful CRISPR treatment trialled in a person

    A genome-editing system more versatile than the classic CRISPR–Cas-9 complex (artist’s illustration) has been trialled in an 18-year-old with a genetic immune disorder.Credit: Laguna Design/Science Photo Library

    The CRISPR family’s most…

    Continue Reading

  • Feasibility of machine learning–based modeling and prediction to assess osteosarcoma outcomes

    Feasibility of machine learning–based modeling and prediction to assess osteosarcoma outcomes

  • Bielack, S. S. et al. Prognostic factors in high-grade osteosarcoma of the extremities or trunk: an analysis of 1,702 patients treated on neoadjuvant cooperative osteosarcoma study group protocols. J. Clin. Oncol. 20 (3), 776–790 (2002).

    • Continue Reading

  • Bridge to a brighter future in fluorescence imaging

    Bridge to a brighter future in fluorescence imaging

    Bridge to a brighter future in fluorescence imaging

    Continue Reading

  • Correction: Dimethyl fumarate promotes the degradation of HNF1B and suppresses the progression of clear cell renal cell carcinoma

    Correction: Dimethyl fumarate promotes the degradation of HNF1B and suppresses the progression of clear cell renal cell carcinoma

    Correction: Dimethyl fumarate promotes the degradation of HNF1B and suppresses the progression of clear cell renal cell carcinoma

    Continue Reading

  • Three distinct strategies lead to programmable aliphatic C−H oxidation in bicyclomycin biosynthesis

    Three distinct strategies lead to programmable aliphatic C−H oxidation in bicyclomycin biosynthesis

  • Abrams, D. J., Provencher, P. A. & Sorensen, E. J. Recent applications of C−H functionalization in complex natural product synthesis. Chem. Soc. Rev. 47, 8925–8967 (2018).

    CAS 
    PubMed 

    Google Scholar 
    …

    • Continue Reading

  • The fast-evolving FIKK kinase family of Plasmodium falciparum can be inhibited by a single compound

    The fast-evolving FIKK kinase family of Plasmodium falciparum can be inhibited by a single compound

    FIKK orthologues in Laverania

    To assess the number of FIKK orthologues in each Laverania species, the word ‘FIKK’ was entered into the search engine of the PlasmoDB website (www.PlasmoDB.org) (release 66) selecting…

    Continue Reading