Wilson, R. S. et al. The natural history of cognitive decline in Alzheimer’s disease. Psychol. Aging 27, 1008–1017 (2012).
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Goedert, M. &…
Category: 5. Biology
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Analysis of the causes of N/P imbalance in mangrove water caused by high elevation shrimp ponds
Results of N and P ratio in water body
It can be seen from the monitoring data in the past 6 years that the TN pollution in the water body of Dongzhai Harbor was relatively serious, while the total phosphorus pollution problem is not significant,…
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Expanding the understanding of DDX3X-related neurodevelopmental disorder in males
Willsey HR, Willsey AJ, Wang B, State MW. Genomics, convergent neuroscience and progress in understanding autism spectrum disorder. Nat Rev Neurosci. 2022;23:323–41.
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Caspase-11 drives macrophage hyperinflammation in models of Polg-related mitochondrial disease
Mouse husbandry and strains
C57BL/6 J (JAX Stock # 000664), PolgD257A/D257A (JAX Stock # 017341), and Ifnar1−/− (JAX Stock # 028256) mice were obtained from The Jackson Laboratory and bred and maintained in multiple vivaria at Texas A&M…
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Histone methyltransferase ASH1L primes metastases and metabolic reprogramming of macrophages in the bone niche
All mouse experimental procedures followed the Institutional Animal Care and Use Committee (IACUC) protocol (#00001955). The mice were housed under a 12-h light/dark cycle, at 68–78 °F with 30–70% humidity. MD Anderson IACUC’s guidelines…
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Multiple infections with Omicron variants increase breadth and potency of Omicron-specific neutralizing antibodies
The breadth and level of cross-reactive antibodies predict protection or reinfection
We conducted a longitudinal study to examine the breadth and cross-reactivity of the antibody response in individuals who have experienced multiple waves of…
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Investigation of the dengue arbovirus in the cities of Bushehr Province through human blood sampling
Study area and population
The study was conducted in Bushehr Province, located in southern Iran. The region was chosen due to its climatic conditions, which are favorable for the proliferation of Aedes mosquitoes, the primary vectors of the dengue…
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Bridging the divide between research and policy
Articles in our May issue discuss how common scientific approaches and datasets could be more useful to policymakers.
The importance of ecology and evolution research to broader biodiversity policy has…
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Long-term engraftment of human stem and progenitor cells for large-scale production of functional immune cells in engineered pigs
Larochelle, A. et al. Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: implications for gene therapy. Nat. Med. 2, 1329–1337 (1996).
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Punica granatum leaf extract as a natural antibacterial agent explored by experimental and computational methods
Antibacterial assay
The in vitro antibacterial efficacy of MPGL extract against the gram-negative human pathogenic bacteria E. coli (ATCC25922) was evaluated using agar disc diffusion method. MPGL extract revealed varying patterns of antibacterial…
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