Category: 5. Biology

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  • Molecular basis of positional memory in limb regeneration

    Molecular basis of positional memory in limb regeneration

    Ethics oversight

    All animal experiments were approved by the Magistrate of Vienna (Genetically Modified Organism Office and MA58, City of Vienna, Austria), under licences GZ: 51072/2019/16, GZ: MA58-1432587-2022-12 and GZ: MA58-1516101-2023-21.

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  • RNA splicing — a central layer of gene regulation

    Technological and computational advances in recent years, from cryo-electron microscopy to sequencing technologies and machine learning, have substantially deepened our understanding of RNA splicing. Nature Reviews Genetics and Nature Reviews…

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  • Global DNA methylation differences involving germline structural variation impact gene expression in pediatric brain tumors

    Global DNA methylation differences involving germline structural variation impact gene expression in pediatric brain tumors

    Patient cohorts

    Results are based on data generated by the CBTN. Patients were consented by one of 32 participating sites and enrolled on a local IRB-approved protocol which includes key language to enable prospective collection of, future…

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  • Enabling RNA-compatible synthetic receptors through RNA editing

    Enabling RNA-compatible synthetic receptors through RNA editing

    Competing interests

    X.Z. and L.S.M.-F. are co-inventors on a US provisional patent application no. 63/399,400, relating sense-and-response of proteins, peptides and small molecules using ligand-induced…

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  • Enhanced antiviral innate immunity supports the bat reservoir of Marburg virus

    Enhanced antiviral innate immunity supports the bat reservoir of Marburg virus

    Enhanced antiviral innate immunity supports the bat reservoir of Marburg virus

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  • Sequence diversity lost in early pregnancy

    Sequence diversity lost in early pregnancy

    Cohort

    The COPL study is a prospective cohort study, with the first patients recruited in November 2020 (described in detail previously20). Women with a confirmed or suspected pregnancy loss were referred by a physician to a gynaecological…

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  • The yin yang of transcriptional memory

    The yin yang of transcriptional memory

    The yin yang of transcriptional memory

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  • Transcriptomic analysis of CDL-gated photoperiodic flowering mechanisms in cannabis and their responsiveness to R: FR ratios in controlled environment agriculture

    Transcriptomic analysis of CDL-gated photoperiodic flowering mechanisms in cannabis and their responsiveness to R: FR ratios in controlled environment agriculture

  • Cheng, M.-C., Kathare, P. K., Paik, I. & Huq, E. Phytochrome Signaling Networks. Annu. Rev. Plant Biol. 72, 217–244 (2021).

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  • Reveal genomic insights into cotton domestication and improvement using gene level functional haplotype-based GWAS

    Reveal genomic insights into cotton domestication and improvement using gene level functional haplotype-based GWAS

    Mining of gene-level functional haplotype

    We collected a total of 4392 upland cotton cultivars and lines (accessions) of G. hirsutum from four of our previously published datasets, as well as four other publicly available datasets (Supplementary…

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