Category: 5. Biology

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  • CTLA-4 expression on tregs is needed for suppression of autoimmune uveitis

    CTLA-4 expression on tregs is needed for suppression of autoimmune uveitis

    Utilizing a CD4-specific deletion of CTLA-4, we determined the impact of a CTLA-4 deficiency on CD4+ T cells on EAU. We observed a delay in resolution of EAU in mice with a CD4+ T cell deficiency for CTLA-4. We further observed that a deletion of…

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  • Limocitrin induced cellular death through ERK pathways in human oral squamous cell cancer

    Limocitrin induced cellular death through ERK pathways in human oral squamous cell cancer

    Cell culture

    Human OSCC cell lines SCC-47 and SCC-9 were selected for experimentation. The cell lines were purchased from the Japanese Collection of Research Bioresource Cell Bank (Shinjuku, Japan). SCC-47 and SCC-9 were cultured in Dulbecco’s…

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  • Author Correction: A substrate binding model for the KEOPS tRNA modifying complex

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  • JMY powers dendritogenesis and is regulated by CaM revealing a general, critical principle in neuromorphogenesis

    JMY powers dendritogenesis and is regulated by CaM revealing a general, critical principle in neuromorphogenesis

    JMY powers dendritogenesis and is regulated by CaM revealing a general, critical principle in neuromorphogenesis

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  • Revealing 3D microanatomical structures of unlabeled thick cancer tissues using holotomography and virtual H&E staining

    Revealing 3D microanatomical structures of unlabeled thick cancer tissues using holotomography and virtual H&E staining

    Network training

    To train the network, we prepared the paired training dataset from a 4 μm-thick, H&E-stained colon cancer tissue slide (Fig. 2a). Initially, we utilized holotomography to capture both the 3D RI images and 2D single-channel BF…

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  • From field to analysis: strengthening reproducibility and confirmation in research for sustainable agriculture

  • Ioannidis, J. P. A. Why most published research findings are false. PLOS Med. 2, e124 (2005).

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  • Baker, M. 1500 scientists lift the lid on reproducibility. Nature 533, 452–454…

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  • Clown Anemonefish Shrink to Survive Heat Stress, New Study Says

    Clown Anemonefish Shrink to Survive Heat Stress, New Study Says

    Recognizable from the starring role in the film ‘Finding Nemo,’ the clown anemonefish (Amphiprion percula) also shrink in order to avoid social conflict, according to a paper published in the journal Science Advances.

    Versteeg et al….

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  • Labroots 2025 Cannabis Sciences Poster Winner: Dr. Flor Ortiz and Dr. Mish Castillo

    Labroots 2025 Cannabis Sciences Poster Winner: Dr. Flor Ortiz and Dr. Mish Castillo

    Labroots’ virtual events enable individuals worldwide to connect and engage in groundbreaking scientific research from your scientific discipline or similar interests. These virtual events offer a poster…

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  • Plant cell sculptors | ScienceDaily

    Plant cell sculptors | ScienceDaily

    New research from the Sainsbury Laboratory at the University of Cambridge has shed light on how plants precisely control their growth and development, revealing that seemingly similar molecular components fulfil surprisingly different jobs.

    The…

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