Clinicopathological and immunohistochemical data
The median age was 64 years (range, 36–86 years), and 44 of the 87 patients were male (51%). Distal pancreatectomy, pancreatoduodenectomy, and central pancreatectomy were performed for 41 (47%),…
Category: 5. Biology
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Monoacylglycerol acyltransferase maintains ionotropic receptor expression for cool temperature sensing and avoidance in Drosophila
Li, K. & Gong, Z. Feeling hot and cold: thermal sensation in Drosophila. Neurosci. Bull. 33, 317–322 (2017).
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Rohacs, T., Thyagarajan, B. & Lukacs, V. Phospholipase…
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Disulfide bond-related gene signature development for bladder cancer prognosis prediction and immune microenvironment characterization
Identification of prognostic genes associated with disulfide in BLCA
A total of 407 DEGs were identified from TCGA-BLCA, filtered by |Log2FC| ≥ 1.5 and p-value < 0.05 (Supplementary Fig. 1A). Subsequently, an intersection with the disulfide…
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Investigation and design of the dual specificity of the PRDM9 protein lysine methyltransferase
PRDM9 expression and purification
His-tagged PRDM9 was overexpressed and purified using Ni-NTA affinity chromatography (Fig. 1b). To test the activity of the purified enzyme, SPOT peptide array methylation experiments were performed using H3K4…
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Cell-context response to germ layer differentiation signals is predetermined by the epigenome in regionalized epiblast populations
FGF/ERK profiles distinguish anterior and distal posterior epiblast
Post-implantation epiblast cells have a predetermined regionalized bias5 towards specific germ layers that is associated with gradients of FGF523 and epithelial markers10, both…
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Blockchain based electronic educational document management with role-based access control using machine learning model
For word embedding models, we use the word2vec framework for training. The framework implements two distinct models and training methodologies. The first method, the Continuous Bag-Of-Words (CBOW) technique, attempts to anticipate a word by using…
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Author Correction: Longitudinal profiling of low-abundance strains in microbiomes with ChronoStrain
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format,…
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Transcriptomic response of marine dinoflagellate Prorocentrum cordatum to phosphorus deficiency
Paytan, A. & McLaughlin, K. The oceanic phosphorus cycle. Chem. Rev. 107, 563–576 (2007).
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Cooper, G. M. The Cell: A Molecular Approach (Sinauer…
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Microorganisms thriving together as communities
This Genome Watch article discusses the dominance of uncultivated microorganisms in natural ecosystems and how the consequent genome-driven insights could guide the rational design of synthetic microbial communities.
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Macroecological patterns of planktonic unicellular eukaryotes richness in the Southeast Pacific Ocean
Sutherland, W. J. et al. Identification of 100 fundamental ecological questions. J. Ecol. 101, 58–67 (2013).
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Geisen, S. et al. Soil protistology rebooted: 30 fundamental…
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