Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or…
Category: 5. Biology
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Human endothelial cells promote a human neural stem cell type B phenotype via Notch signaling
Cell culture
Human fetal brain-derived neural stem/progenitor cells were isolated from cadaveric brain cortices and designated as SC27 (male, 23 weeks gestation), SC30 (male, 25 weeks gestation), and SC23 (male, 23 weeks gestation)95. Use of human…
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Validation of the Finnish MD Anderson Dysphagia Inventory (MDADI) in patients with head and neck cancer
Sung, H. et al. Global Cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J. Clin. 71, 209–249. https://doi.org/10.3322/CAAC.21660 (2021).
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Stepwise strategy for generating human trophoblast stem-like cells from embryonic stem cells reveals specific role of TFAP2C in acquiring self-renewability
ESC culture
All experiments using the human ESC lines were performed following the human ESC guidelines of the Japanese government. Human ESC lines used in this study, KhES-1 and KthES-13, were established from donated human embryos by researchers…
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Deep learning-driven automated mitochondrial segmentation for analysis of complex transmission electron microscopy images
Probabilistic interactive segmentation and mask-based auto quantification
Our pipeline for mitochondrial morphology analysis was developed using a probabilistic interactive segmentation model combined with a mask-based automated quantification…
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Antibiotics re-booted—time to kick back against drug resistance
Waring, M. J. et al. An analysis of the attrition of drug candidates from four major pharmaceutical companies. Nat. Rev. Drug Discov. 14, 475 (2015).
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The value of GULP1 in cancer prognosis and immunotherapy, validated from pan-cancer analysis to pancreatic cancer
Expression and subcellular localization of GULP1
See supplementary Table 1 for tumor abbreviations. We first analyzed GULP1 expression in normal tissues and found that GULP1 mRNA (Fig. 1a) and protein (Fig. 1f) were highly expressed in normal…
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Author Correction: Transcriptomic profiling of individual bacteria by MATQ-seq
Author Correction: Transcriptomic profiling of individual bacteria by MATQ-seq
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Mapping grey and white matter activity in the human brain with isotropic ADC-fMRI
Ogawa, S., Lee, T.-M., Kay, A. R. & Tank, D. W. Brain magnetic resonance imaging with contrast dependent on blood oxygenation. Proc. Natl Acad. Sci. 87, 9868–9872 (1990).
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Transcriptomic analysis reveals molecular mechanism by which Chinese olive fruit prolongs lifespan of Caenorhabditis elegans
Effects of COFE on survival time, body length, body width, locomotion capacity, lipofuscin, and stress resistance of C. elegans
Totally, 34 substances were detected from the COFE, of which the main polyphenols were gallic…
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