Jin, M. et al. Genetic signatures of selection for cashmere traits in Chinese goats. Animals (Basel) 10 https://doi.org/10.3390/ani10101905 (2020).
Zhang, Y. et al. Transcriptome profiling reveals transcriptional and alternative splicing…
Category: 5. Biology
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Knowing when to fold ’em
The emergence of chemical probing methods based on mutational profiling, like SHAPE-MaP and DMS-MaPseq, has given researchers the capacity to capture ensemble information about RNA structure. However, interpreting those results requires…
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Hyperimmune serum containing Histophilus somni rHsp60, rOMP40 and Actinobacillus pleuropneumoniae LPS antibodies as supplementary treatment for calf respiratory diseases
Overton, M. W. Economics of respiratory disease in dairy replacement heifers. Anim. Health Res. Rev. 21, 143–148 (2020).
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Furman-Fratczak, K., Rzasa, A. & Stefaniak,…
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Remodeling and retooling metabolism | Nature Chemical Biology
Chemical biology approaches have enhanced metabolism research through the detection of key metabolites and altering enzymatic reactions. This themed issue features a collection of articles that explore emerging research areas in the continual…
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Identification of covalent inhibitors of Staphylococcus aureus serine hydrolases important for virulence and biofilm formation
Serine-based covalent fragment library screening
To establish a setup for identifying selective inhibitors for each target Fph enzyme, we developed a high-throughput screen (HTS) using a fluorescent-based enzyme assay. For each of the three…
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Author Correction: Differential response of tissue engineered skeletal muscle from rheumatoid arthritis patients and healthy controls
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or…
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Human endothelial cells promote a human neural stem cell type B phenotype via Notch signaling
Cell culture
Human fetal brain-derived neural stem/progenitor cells were isolated from cadaveric brain cortices and designated as SC27 (male, 23 weeks gestation), SC30 (male, 25 weeks gestation), and SC23 (male, 23 weeks gestation)95. Use of human…
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Validation of the Finnish MD Anderson Dysphagia Inventory (MDADI) in patients with head and neck cancer
Sung, H. et al. Global Cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J. Clin. 71, 209–249. https://doi.org/10.3322/CAAC.21660 (2021).
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Stepwise strategy for generating human trophoblast stem-like cells from embryonic stem cells reveals specific role of TFAP2C in acquiring self-renewability
ESC culture
All experiments using the human ESC lines were performed following the human ESC guidelines of the Japanese government. Human ESC lines used in this study, KhES-1 and KthES-13, were established from donated human embryos by researchers…
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Deep learning-driven automated mitochondrial segmentation for analysis of complex transmission electron microscopy images
Probabilistic interactive segmentation and mask-based auto quantification
Our pipeline for mitochondrial morphology analysis was developed using a probabilistic interactive segmentation model combined with a mask-based automated quantification…
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