Category: 5. Biology

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  • Building bridges for autophagy

    Building bridges for autophagy

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  • Novel atypical G protein-coupled receptor (GPCR)-arrestin complexes: a structural snapshot of the barcode hypothesis

    Novel atypical G protein-coupled receptor (GPCR)-arrestin complexes: a structural snapshot of the barcode hypothesis

    In a recent study published in Nature by Chen et al., six novel cryo-EM structures of atypical chemokine receptor 3 (ACKR3) complexes with Arrestin2 (Arr2, also known as β-arrestin1) and Arrestin3…

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  • Same same but different | Nature Reviews Cancer

    Same same but different | Nature Reviews Cancer

    Chemotherapies such as cytarabine can cause neurotoxicity, whereas others such as gemcitabine are well tolerated, despite both being nucleoside analogues capable of crossing the blood–brain barrier. Both drugs are known to induce single-strand…

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  • Unravelling cellular interactions using flow cytometry

    Unravelling cellular interactions using flow cytometry

    Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

    This is a summary of: Vonficht, D. et al. Ultra-high-scale cytometry-based cellular interaction mapping. Nat….

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  • Spatiotemporal lipidomics in living tissue

    Spatiotemporal lipidomics in living tissue

    Typical spatial biology experiments are destructive or are performed on non-living tissue. However, there is growing interest in being able to monitor biology in action. A team of researchers from King’s College London led by Ciro Chiappini has…

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  • Ultra-high-scale cytometry-based cellular interaction mapping

    Ultra-high-scale cytometry-based cellular interaction mapping

    Animals

    Unless otherwise stated, animal experiments were conducted under German law and approved by Regierungspräsidium Karlsruhe (approval numbers DKFZ299, G-55/20, G-56/20) or the Landesamt für Gesundheit und Soziales in Berlin (LAGeSo,…

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  • Effects of natural Lithium and Lithium isotopes on voltage gated sodium channel activity in SH-SY5Y and IPSC derived cortical neurons

    Effects of natural Lithium and Lithium isotopes on voltage gated sodium channel activity in SH-SY5Y and IPSC derived cortical neurons

    SH-SY5Y and iPSC-derived cortical neurons maintenance

    SH-SY5Y cells were cultured as previously described29 with some modifications described below. Briefly, the cells were maintained at 37 °C in Dulbecco’s Modified Eagle’s Medium…

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  • The biofouling tubeworm Hydroides elegans

    The biofouling tubeworm Hydroides elegans

    The biofouling tubeworm Hydroides elegans

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