RNA helicase unravels the secrets of germ granules
Category: 5. Biology
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RNA helicase unravels the secrets of germ granules
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Astrocyte inflammasomes | Nature Immunology
Neuronal synaptic plasticity in the hippocampus is required for the formation of new neuronal connections during memory formation. In Immunity, Zengeler et al. report that inflammasome activation in hippocampus astrocytes regulates hippocampal…
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Milk NIR spectroscopy and Aquaphotomics novel diagnostic approach to Paratuberculosis in dairy cattle
Mycobacterium avium subspecies Paratuberculosis (MAP), a member of the Mycobacterium avium complex, causes Paratuberculosis or Johne’s disease (JD), a contagious, chronic, and usually fatal infection. Johne’s disease is classified as a group…
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NOTCH1 signaling is dysregulated by loss of the deubiquitinase USP28 with del(11q), uncovering USP28 inhibition as novel therapeutic target in CLL
Döhner H, Stilgenbauer S, Benner A, Leupolt E, Kröber A, Bullinger L, et al. Genomic aberrations and survival in chronic lymphocytic leukemia. N Engl J Med. 2000;343:1910–6.
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Contrasting clonal and population genetic structure in two endangered Costa Rican Vanilla species of commercial interest
In our studies, the clonal nature of V. odorata and V. pompona has proven to be a critical factor in understanding the amount and distribution of genetic diversity. In comparing V. odorata and V. pompona, our study highlights sharp differences in…
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Correction: DNA damage-induced translocation of mitochondrial factor HIGD1A into the nucleus regulates homologous recombination and radio/chemo-sensitivity
Correction: DNA damage-induced translocation of mitochondrial factor HIGD1A into the nucleus regulates homologous recombination and radio/chemo-sensitivity
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GDNF overexpression in astrocytes enhances branching and partially preserves hippocampal function in an Alzheimer’s rat model
Brandebura, A. N., Paumier, A., Onur, T. S. & Allen, N. J. Astrocyte contribution to dysfunction, risk and progression in neurodegenerative disorders. Nat. Rev. Neurosci. 24, 23–39 (2023).
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High mobility group A1 (HMGA1) promotes esophageal squamous cell carcinoma progression by inhibiting STING-mediated anti-tumor immunity
HMGA1 Inhibits the Expression of ISGs in ESCC Cells
To investigate the role of HMGA1 in the tumorigenesis and development of ESCC, we first assessed HMGA1 expression in various human ESCC cell lines. HMGA1 expression was found to be significantly…
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The late rise of sky-island vegetation in the European Alps
Hoorn, C. et al. Amazonia through time: Andean uplift, climate change, landscape evolution, and biodiversity. Science 330, 927–931 (2010).
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Feijó, A. et…
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Polymerised superparamagnetic antigen presenting cell lymphocyte capture for enriching tumour reactive T-cells and neoantigen identification
Ethics statement
All experiments involving animals were conducted following experimental protocols approved by the Academia Sinica Institutional Animal Care and Utilization Committee, Academia Sinica, Taipei, Taiwan (#15-10-868). Mice were housed…
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