Category: 5. Biology

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  • Trans-RNAs to program translation initiation

    Trans-RNAs to program translation initiation

    Translation of upstream open reading frames (uORFs) in mRNAs with multiple start codons can suppress downstream initiation sites. The researchers designed antisense RNA oligonucleotides (oligos) with a functional 5′ cap to bypass uORFs, which…

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  • The effects of LINC00324 on cell proliferation, migration, and invasion via autophagy in melanoma

  • Wei, C. Y. et al. Bioinformatics-based analysis reveals elevated MFSD12 as a key promoter of cell proliferation and a potential therapeutic target in melanoma. Oncogene 38(11), 1876–1891 (2019).

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  • Environmental metagenomics enhances detection of circulating viruses from live poultry markets in Cambodia

  • Peccia, J. et al. Measurement of SARS-CoV-2 RNA in wastewater tracks community infection dynamics. Nat. Biotechnol. 2020 38, 1164–1167 (2020).

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  • Coker, R. J., Hunter, B. M., Rudge, J. W.,…

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