Cell cultivation
Human Bone Marrow derived Mesenchymal Stromal Cells (hBM-MSCs) (Cat.: C-12974, Lot.: 438Z012.1) and Normal Human Dermal Fibroblasts (NHDFs) (Cat.: C-12302, Lot.: 412Z029.2) at passage 2 (P2) were purchased from PromoCell, Germany….
Category: 5. Biology
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Resurrecting a miniature Cas9 ancestor for genome and epigenome editing
Competing interests
C.A.G. is a co-founder of Tune Therapeutics and Locus Biosciences, and an advisor to Tune Therapeutics and Sarepta Therapeutics. C.A.G. and G.L.B. are inventors on patent applications…
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Conditioned versus innate effort-based tasks reveal divergence in antidepressant effect on motivational state in male mice
Acute SSRI treatment exerts opposing effects in the Effort for Reward and Effort-Based Foraging task
Escitalopram reduced nesting material shuttled (Q = 29.00, p < 0.0001, (3 mg/kg, p = 0.0024), (10 mg/kg, p < 0.0001)) in the…
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High CD36 expression in the tumor microenvironmental vasculature correlates with unfavorable overall survival in high grade serous ovarian cancer
We performed an analysis of CD36 expression in tumor tissues of EOC patients. CD36 expression was predominantly found on tumor vasculature. CD36 positive tumor vasculature was significantly associated with unfavorable overall survival in HGSOC…
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Daniel Aberdam, the legacy of a mentor
Daniel Aberdam (1954–2025)
If I should go tomorrow It would never be goodbye, For I have left my heart with you (Anon)
It is with profound sadness that we announce the passing…
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Versatile tethering system to control cell-specific targeting of bioengineered extracellular vesicles
Cell culture
HeLa wild-type are from ATCC, SK-OV-3 constitutively express mCherry and were a gift from Zelia Gouveia and Franck Perez, and A-431 were a gift from Giulio Avveduto. HeLa – wild-type and stably genetically modified – and A-431…
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Scientists Identify Genetic Variants Associated with Increased Purring in Cats
Cats (Felis catus) are companions familiar to people worldwide. Despite their popularity, few studies have investigated the genetic background of their behavior. In a new study, a team of researchers at Wildlife Research Center of Kyoto…
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The sweet spot: sugar-based sensors to revolutionize snake venom detection
Every five minutes, 50 people are bitten by a snake worldwide; four will be permanently disabled and one will die. In the time-critical situation following a bite, identifying the snake venom making its way through your system is vital to saving…
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Nitrogen loss on sandy shores: The big impact of tiny anoxic pockets
Denitrification in tiny anoxic pockets on sand grains could account for up to one-third of total nitrogen loss in silicate shelf sands.
Some microbes living on sand grains use up all the oxygen around them. Their neighbors, left without oxygen,…
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Researchers genetically altered fruit flies to crave cocaine
In a world first, scientists at the University of Utah have engineered fruit…
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