LabGenius Therapeutics (“LabGenius”) is a drug discovery company combining machine learning (ML) and high-throughput experimentation to optimize complex therapeutic antibodies, including those with multispecific designs. The…
Category: 5. Biology
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Mediterranean Diet Relieves IBS Symptoms in Pilot Study
The Mediterranean diet relieves symptoms of irritable bowel syndrome, however the low FODMAP diet still produces better results. The corresponding study was published in Neurogastroenterology &…
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Early brain wiring holds clues to infant emotional development
In a comprehensive Genomic Press research article, scientists have uncovered remarkable insights into how the earliest brain connections shape infant emotional development, potentially offering new ways to identify children at risk…
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The effects of inhibiting IRE1α on the viability of ovarian granulosa cells
Cells and ethical approval
In this study, the human granulosa cell line (SVOG) (BeNa Culture Collection, BNCC340889) was established by transfecting primary human granulosa cells (hGL) with the non-tumorigenic immortalized SV40 large T antigen….
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Androgens inhibit protective CD8+ T cell responses against pre-erythrocytic malaria parasites in mice
Male mice exhibit less protection after prime-and-trap vaccination
To assess the influence of sex on the efficacy on liver stage malaria vaccines, we utilized a two-dose heterologous P&T regimen16 in male and female BALB/cJ mice. This P&T regimen…
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Single-molecule parallel analysis for rapid exploration of sequence space
Roy, R., Hohng, S. & Ha, T. A practical guide to single-molecule FRET. Nat. Methods 5, 507–516 (2008).
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Joo, C., Balci, H., Ishitsuka,…
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Distinct modulation of microsaccades in motor planning and covert attention
Posner, M. I. Orienting of attention. Q. J. Exp. Psychol. 32, 3–25 (1980).
Carrasco, M. Visual attention: The past 25 years. Vis. Res. 51, 1484–1525 (2011).
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RIOK1 phase separation restricts PTEN translation via stress granules activating tumor growth in hepatocellular carcinoma
Sung, H. et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA 71, 209–249 (2021).
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Yang, C. et al….
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Exceptionally low genomic diversity in the underutilised legume Kersting’s groundnut
Schmidhuber, J. & Tubiello, F. N. Global food security under climate change. Proc. Natl. Acad. Sci. USA 104, 19703–19708 (2007).
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ICRF193 potentiates the genotoxicity of etoposide
Assay optimization for co-treatment of ICRF193 in a 1536 well plate format
We aimed to identify compounds that have synergistic effects with ICRF193 in the in vitro primary screening. We hypothesized that if ICRF193 potentiates the compound’s…
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