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Category: 5. Biology
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Dopamine says do that again
Repeated actions may be reinforced through action prediction error — the difference between an executed action and its prediction given a particular state — but experimental evidence for such a movement-based, value-free teaching signal has…
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Correction: Dissociable effects of psilocybin and escitalopram for depression on processing of musical surprises
Correction: Dissociable effects of psilocybin and escitalopram for depression on processing of musical surprises
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Tuning arousal | Nature Neuroscience
The locus coeruleus (LC), a major source of noradrenaline in the brain, plays a crucial role in regulating arousal and behavior. Despite its known functions, the mechanisms that control LC activity, particularly the influence of local GABAergic…
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Uncovering global genetic diversity for equitable precision medicine
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Following the Human Genome Project, it became clear that a comprehensive catalogue of human genetic variation was essential for understanding disease risk and adaptation. Efforts like the HapMap and 1000 Genomes…
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End-to-end topographic networks as models of cortical map formation and human visual behaviour
Neural network architectures and training
All-TNNs
All-TNNs are implemented on the basis of LCNs—that is, ANNs that are identical to CNNs except that no weight sharing is performed (that is, weight kernels are independent across space). In…
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An intriguing role of repeat-element RNAs in nerve injury repair
Following peripheral nerve injury, a variety of intrinsic cellular and molecular mechanisms are engaged to initiate repair and regeneration. These mechanisms include RNA localization to the region of injury and local translation, but how these…
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Older Adults Increasingly Turning to Marijuana, Especially in Legal States
What patterns does cannabis use have for older adults? This is what a recent study published in JAMA Internal Medicine hopes to address as a team of researchers investigated increased cannabis use for older…
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Reverse transcriptase activity found in aging and Alzheimer’s brains
Alzheimer’s disease is the most common cause of dementia and affects more than a tenth of Americans aged 65 and older. The disease has proven difficult to develop new treatments for, and available treatment options are limited. With…
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New anti-aging compounds found hidden beneath the skin
People go to great lengths to maintain youthful-looking skin with masks, creams and serums. Now, researchers have discovered compounds with anti-aging properties hidden beneath our own skin. The three molecules, produced by a…
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