Model formulation
This study applies the concepts from20,21 to formulate a mathematical model for analysing the dynamics of BBTD incorporating disease resistance components. Banana plants and aphid vector populations are considered in the…
Category: 5. Biology
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CellNEST reveals cell–cell relay networks using attention mechanisms on spatial transcriptomics
CellNEST infers communication in spatial transcriptomic data
Ligand–receptor pair-based communication depends on spatial distance; however, the majority of existing tools do not leverage positional information to detect CCC and collapse…
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Inhibition of levodopa metabolism to dopamine by honokiol short-chain fatty acid derivatives may enhance therapeutic efficacy in Parkinson’s disease
Chen, H. H. et al. Therapeutic effects of Honokiol on motor impairment in Hemiparkinsonian mice are associated with reversing neurodegeneration and targeting PPARγ regulation. Biomed. Pharmacother. 108, 254–262.
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Computational discovery of novel aryl hydrocarbon receptor modulators for psoriasis therapy
Larigot, L., Juricek, L., Dairou, J. & Coumoul, X. AhR signaling pathways and regulatory functions. Biochim. Open. 7, 1–9 (2018).
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Esser, C. &…
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Value-free teaching in action | Nature Reviews Neuroscience
Dopamine neuron activity reinforces actions that lead to reward via reward prediction errors (RPEs). Movement-related activity of striatal dopamine neurons has also been hypothesized to encode action prediction errors (APEs) — discrepancies…
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Developmental features and unique characteristics of peptide-specific PLZF+ innate-like T cells in mice
Transcriptional landscape of thymic PILT cell-enriched population
In analytical flow cytometry, PILT cells are identified by gating on TCRβ+PLZF+ T cell population after excluding other T cell subsets known to express PLZF, such as iNKT, MAIT and…
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Identifying ecological thresholds from functional traits for optimal ecosystem management
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This is a summary of: Le Bagousse-Pinguet, Y. et al. Thresholds of functional trait diversity driven by land…
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PTPN2 inhibits TG-induced ERS-initiated TNBC apoptosis through the mitochondrial pathway
Siegel, R. L., Miller, K. D., Wagle, N. S. & Jemal, A. Cancer statistics, 2023. CA Cancer J. Clin. 73(1), 17–48 (2023).
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Garrido-Castro, A. C., Lin, N. U. & Polyak,…
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Personalized, in vivo gene editing for a newborn
- RESEARCH HIGHLIGHT
Researchers develop a personalized base-editing therapy…
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Sleep cycles process memories | Nature Neuroscience
Memory replay during sleep probably facilitates the transfer of memories from intermediate storage in the hippocampus to long-term storage in the cortex. In a paper published in Neuron, Bollmann, Baracskay et al. reveal that memories are not…
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