Stretching along the Brazilian coastline, the Atlantic Forest is home to hundreds of species of birds, amphibians, reptiles, mammals, and fishes. However, due to human expansion, only about a third of the forest’s original area remains intact.
Category: 5. Biology
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Mosquitoes' thirst for human blood has increased as biodiversity loss worsens
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Without forests, mosquitoes turn to human blood
If you’re someone who mosquitoes just adore, we feel your pain. Unfortunately,…
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MIT researchers map dynamic fuzzy coat surrounding tau protein fibrils
One of the hallmarks of Alzheimer’s disease is the clumping of proteins called Tau, which form tangled fibrils in the brain. The more severe the clumping, the more advanced the disease is.
The Tau protein, which has also been…
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Polyamines reshape protein phosphorylation to guide key cellular fate decisions
Polyamines are small molecules naturally present in all cells and are critical in guiding cellular decisions, whereas an alteration in the abundance of these metabolites is invariably observed in pathological scenarios such as…
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New chemistry revives neurokinin-1 receptor as depression treatment target
For decades, scientists have investigated the neurokinin-1 receptor (NK1R) as a potential target for treating major depressive disorder. Early studies suggested promise, but enthusiasm faded after clinical trials of drugs such as…
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H3K27me3-dependent imprinting and transcriptional regulation in early mouse embryos requires EZHIP-mediated restriction of PRC2 activity
Xu, Q. & Xie, W. Epigenome in Early Mammalian Development: Inheritance, Reprogramming and Establishment. Trends Cell Biol. 28, 237–253 (2018).
Tucci, V., Isles, A. R., Kelsey, G.,…
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Control of telomerase recruitment and end protection by independent shelterin components
Blackburn, E. H. Switching and signaling at the telomere. Cell 106, 661–673 (2001).
Bianchi, A. & Shore, D. How telomerase reaches its end: mechanism of telomerase regulation by the telomeric…
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The microbiome at the centre of NAD+ supplementation
The microbiome at the centre of NAD+ supplementation
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Metabolic adaptation in CD4+ T cells promotes immunosuppression in sepsis
Metabolic adaptation in CD4+ T cells promotes immunosuppression in sepsis
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Inferring chromatin architecture at a single locus through probabilistic in situ DNA localization
Hug, C. B., Grimaldi, A. G., Kruse, K. & Vaquerizas, J. M. Chromatin Architecture Emerges During Zygotic Genome Activation Independent Of Transcription. Cell 169, 216–228.e19 (2017).
Nora, E….
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