Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
This is a summary of: Yu, J. et al. Programmable RNA acetylation with CRISPR–Cas13. Nat. Chem. Biol.
Category: 5. Biology
-
Targeted RNA acetylation via a dCas13-guided engineered acetyl-transferase
-
Pioneer factor ETV2 safeguards endothelial cell specification by recruiting the repressor REST to restrict alternative lineage commitment
Wang, K. et al. Robust differentiation of human pluripotent stem cells into endothelial cells via temporal modulation of ETV2 with modified mRNA. Sci. Adv. https://doi.org/10.1126/sciadv.aba7606 (2020).
Lai, W. K. M. & Pugh, B. F. Understanding…
Continue Reading
-
Iterative transcription factor screening enables rapid generation of microglia-like cells from human iPSC
Barcoded TF expression vector construction
All TFs used in this study were obtained from the TFome collection2 in pDONR format. For expression in hiPSCs, a PiggyBac integrating Dox-inducible vector pBAN2 was used. To create barcoded pBAN…
Continue Reading
-
Author Correction: Segment Anything for Microscopy
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate…
Continue Reading
-
Author Correction: The genomic landscape of gene-level structural variations in Japanese and global soybean Glycine max cultivars
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format,…
Continue Reading
-
Haplotype-resolved chromosome-level genome assembly of Fragaria × ananassa Duch. cv. ‘Yuexin’
Sample collection
The strawberry (Fragaria × ananassa) cultivar ‘Yuexin’ (2n = 8x = 56) was used for genome sequencing. Plants were grown in the greenhouse of the Zijingang Campus at Zhejiang University (Zhejiang, China). Young…
Continue Reading
-
Polygenic prediction of cellular immune responses to mumps vaccine
Centers for Disease Control and Prevention. Mumps cases and outbreaks. US: Centers for Disease Control and Prevention; 2022.
Ovsyannikova IG, Haralambieva IH, Schaid DJ, Warner ND, Poland GA, Kennedy RB. Genome-wide determinants of cellular immune…
Continue Reading
-
Viral evolution prediction identifies broadly neutralizing antibodies to existing and prospective SARS-CoV-2 variants
Ethics statement
Use of authentic SARS-CoV-2 virus strains was undertaken with the approval of the Institutional Biosafety Committee of the Beijing Key Laboratory for Animal Models of Emerging and Remerging Infectious Diseases (application number…
Continue Reading
-
HPV status impacts oncobacteria abundance and prognostic relevance in head and neck squamous cell carcinoma
Weatherspoon DJ, Chattopadhyay A, Boroumand S, Garcia AI. Oral cavity and oropharyngeal cancer incidence trends and disparities in the United States: 2000–2010. Cancer Epidemiol. 2015;39:497–504.
…
Continue Reading
-
Unraveling Alzheimer’s complexity with a distinct Aβ42 fibril type and specific AV-45 binding
Goedert, M. & Spillantini, M. G. A century of Alzheimer’s disease. Science 314, 777–781 (2006).
Google Scholar
McKhann, G. et al. Clinical diagnosis of Alzheimer’s…
Continue Reading