Stanton, B. Z., Chory, E. J. & Crabtree, G. R. Chemically induced proximity in biology and medicine. Science 359 (2018).
Glasgow, A. A. et al. Computational design of a modular protein sense-response system. Science 366, 1024–1028 (2019).
Category: 5. Biology
-
The SjD Map: an interactive pathway tour into Sjögren’s disease signalling mechanisms
Beydon, M. et al. Impact of patient ancestry on heterogeneity of Sjögren’s disease. RMD Open. Mars 9, e002955 (2023).
Thurtle, E. et al. Epidemiology of Sjögren’s: a systematic literature…
Continue Reading
-
NUP93 facilitates the nuclear import of SOX2 to activate G3BP1 transcription and impairs gemcitabine response in pancreatic cancer
Siegel RL, Kratzer TB, Giaquinto AN, Sung H, Jemal A. Cancer statistics, 2025. CA Cancer J Clin. 2025;75:10–45.
Mizrahi JD, Surana R, Valle JW, Shroff RT. Pancreatic cancer. Lancet….
Continue Reading
-
Cannabidiphorol (CBDP) acts as a negative allosteric modulator at two distinct sites of cannabinoid receptor 1
Rock, E. M. & Parker, L. A. Constituents of Cannabis sativa. Adv. Exp. Med Biol. 1264, 1–13 (2021).
Yadav, S. P. et al. An overview of phytochemical constituents and pharmacological…
Continue Reading
-
A controllable human spinal cord model with full dorsoventral patterning
Gouti, M., Metzis, V. & Briscoe, J. The route to spinal cord cell types: a tale of signals and switches. Trends Genet. 31, 282–289 (2015).
Sagner, A. & Briscoe, J. Establishing neuronal…
Continue Reading
-
TUFM: a central regulator in mitochondrial quality control and beyond
Richter D, Lipmann F. Separation of mitochondrial and cytoplasmic peptide chain elongation factors from yeast. Biochemistry. 1970;9:5065–70.
Kuhlman P, Palmer JD. Isolation, expression, and…
Continue Reading
-
Neoantigen evolution and response to checkpoint inhibitor immunotherapy in colorectal cancer
Dong, H. et al. Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat. Med. 8, 793–800 (2002).
Ansell, S. M. et al. PD-1 blockade with nivolumab in…
Continue Reading
-
The Sirt2–Nur77 axis regulates muscle stem cell quiescence and senescence via epigenetic–metabolic synergy
Sousa-Victor P, García-Prat L, Muñoz-Cánoves P. Control of satellite cell function in muscle regeneration and its disruption in ageing. Nat Rev Mol Cell Biol. 2022;23:204–26.
Kahn RE,…
Continue Reading
-
Identification of an R2R3-MYB gene regulating tepal background coloration in Tricyrtis sp.
Otani, M. et al. Comprehensive isolation and expression analysis of the flavonoid biosynthesis-related genes in Tricyrtis spp. Biol. Plant. 62, 684–692. https://doi.org/10.1007/s10535-018-0802-7 (2018).
Continue Reading
-
Accumulation of virtual tokens towards a jackpot reward enhances performance and value encoding in dorsal anterior cingulate cortex
Kahneman, D. & Tversky, A. Prospect Theory: An Analysis of Decision under Risk. Econ. Soc. 47, 263–291 (1979).
Anke Braun, X., Urai, A. E., Tobias, X. & Donner, H. Adaptive history biases result from confidence-weighted accumulation of past…
Continue Reading