Category: 5. Biology

Enhanced Genomics (‘Enhanced’ or ‘the Company’), the biotechnology company pioneering 3D multi-omics to rapidly identify high-confidence, genetically validated drug targets for common diseases, today announced the…

Weight loss drugs like Ozempic and Wegovy are used by over 15 million adults in the U.S., or 4.5% of the population. Despite their effectiveness, they have drawbacks. Their effect may not last after discontinuing use, and side…

The International Society for Stem Cell Research (ISSCR) Embryo Models Working Group has released updated recommendations for the oversight and regulation of stem cell-based embryo models (SCBEM), aiming to address rapid…

Human metabolism is a complex web of chemical processes and interactions between our cells and the microbes living within us. The more scientists can identify and classify the molecules involved in our metabolism, called…

Protein expression and purification

The clone for expressing the recombinant HCV sE2 has been described previously^15,18,55. Expression of CHO sE2 and geCHO.sE2.1 and geCHO.sE2.7 was performed as follows. DNA encoding sE2 was chemically transfected…

Signals emanating from the bone marrow microenvironment are crucial for the survival, stem cell self-renewal capacity and pathogenesis of haematological malignancies. Yet, many of the local and direct interactions between stromal cells and…

Cell culture

Human GC MGC803 cells were obtained from Beyotime Biotech (Shanghai, China). Other human GC cell lines (AGS, HGC27, MKN45, SNU-1, and KATOIII) and human mesothelial cell line MET-5A were purchased from Procell Life Science and…

However, guinea pig and human physiologies share several similarities, such as a 6–7 day preimplantation period, cavitation and development of a bilaminar disc after implantation. To establish the guinea pig as a model organism to study human…