arising from S. Li et al. Nature Communications https://doi.org/10.1038/s41467-023-43442-5 (2023)
H–NS is a nucleoid-associated protein involved in chromosome organization and regulation of gene…
Category: 5. Biology
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Clonal hematopoiesis driven by microbial metabolite
“Acquisition of somatic mutations coupled with multiple environmental factors contribute to the expansion of the CHIP clones. Higher levels of CHIP are observed in autoimmune, inflammatory, and in some instances of chronic intestinal…
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A scalable gut epithelial organoid model reveals the genome-wide colonization landscape of a human-adapted pathogen
A scalable human gut epithelium model for Shigella infection
To establish a large-scale human intestinal epithelial model for Shigella infection, we developed a high-throughput gentamicin protection assay, using suspension cultures of enteroids…
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Aging alters the response to CAR T cell therapy
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This is a summary of: Hope, H. C. et al. Age-associated nicotinamide adenine dinucleotide decline drives…
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The maize cis-regulatory landscape | Nature Genetics
Our knowledge about how non-coding genetic variation influences phenotypes in animals has deepened considerably in the last decade. However, plant research in this area has lagged behind. To help fill this gap, Robert Schmitz and colleagues…
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Stable isotopes unveil ocean transport of legacy mercury into Arctic food webs
Spatial trends in sources and pathways
In the peat profiles, Hg stable isotopes reveal significant spatial differences in δ202Hg signatures between Central West Greenland (Qeqertarsuaq) and Northeast Greenland (Zackenberg) (Fig. 1a, b;…
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Author Correction: Larval microbiota primes the Drosophila adult gustatory response
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate…
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Transcription factor binding divergence drives transcriptional and phenotypic variation in maize
Kim, S. & Wysocka, J. Deciphering the multi-scale, quantitative cis-regulatory code. Mol. Cell 83, 373–392 (2023).
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Rodriguez-Leal, D., Lemmon, Z. H., Man,…
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Mendel’s pea traits pinned down
Mendel’s classic studies of inheritance in pea plants focused on seven pairs of contrasting morphological traits. Four of these traits have since been characterized molecularly, but the genetic basis for variation in pod form, pod color and…
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