These authors contributed equally: Jinying Shen, Jing Li, Quan Shen, Jihuan Hou, Chunhe Zhang, Haiqing Bai, Xiaoni Ai.
State key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced…
Category: 5. Biology
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Cellular basis of cephalopod visual abilities
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
This is a summary of: Gavriouchkina, D. et al. A single cell atlas of the bobtail squid visual and nervous…
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Cell-state-specific enhancer design in hematopoiesis
During cellular differentiation, the activity of transcription factors (TFs) changes to regulate the expression patterns of lineage-specific genes. However, it remains unclear how enhancers can transform the activity of an identical set of TFs…
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Detection of Volatile Organic Compounds as an emerging strategy for Parkinson’s disease diagnosis and monitoring
Analytical techniques for VOC detection in PD
Variation in VOC levels in PD have been explored across both pre-clinical and clinical studies with the aim of developing non-invasive tests for diagnosis and/or monitoring. The choice of the…
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Gut ILC2s remember IL-25 | Nature Reviews Immunology
Helminths have evolved complex pathways to create favourable host environments. Through a well-characterized immunoregulatory axis, helminths stimulate gut epithelial tuft cells to produce IL-25, which activates group 2 innate lymphoid cells…
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Genomic landscape of estrogen receptor-positive HER2-negative advanced breast cancer with acquired resistance to aromatase inhibitors: Identification of an ESR1 alteration-related gene signature
SEER [Internet]. [cited 2024 Apr 11]. Female Breast Cancer Subtypes – Cancer Stat Facts. Available from: https://seer.cancer.gov/statfacts/html/breast-subtypes.html.
Burstein HJ. Systemic therapy for estrogen receptor-positive, HER2-negative…
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A new first-line standard-of-care for BRAFV600E-mutated mCRC
The combination of the BRAF inhibitor encorafenib and the anti-EGFR antibody cetuximab is the standard-of-care (SOC) second-line treatment for patients with BRAFV600E-mutated metastatic colorectal cancers (mCRC; 8–12% of patients). Now, results…
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Penetrance of Parkinson’s disease in GBA1 carriers depends on variant severity and polygenic background
In this study, we investigated the combined effect of polygenic background and PD-associated GBA1 variants on the risk of developing PD across two cohorts. Our findings show that both PRSs and GBA1PVs independently contribute to PD risk….
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Protective exercise responses in the dentate gyrus of Alzheimer’s disease mouse model revealed with single-nucleus RNA-sequencing
Buchman, A. S. et al. Total daily physical activity and the risk of AD and cognitive decline in older adults. Neurology 78, 1323–1329 (2012).
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Author Correction: Immune phenotyping of diverse syngeneic murine brain tumors identifies immunologically distinct types
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate…
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