Category: 5. Biology

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  • Bladder cancer variants share aggressive features including a CA125+ cell state and targetable TM4SF1 expression

    Bladder cancer variants share aggressive features including a CA125+ cell state and targetable TM4SF1 expression

    Sample collection

    All bladder tumor samples used in our analyses were obtained in compliance with ethical regulations under University of California San Francisco IRB 10-04057. Informed consent was obtained from all participants or their legally…

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  • Identification of an immunomodulatory lncRNA signature associated with immune cell reprogramming in high-grade glioma

    Identification of an immunomodulatory lncRNA signature associated with immune cell reprogramming in high-grade glioma

    Analysis of TIME from different glioma models revealed distinct lncRNA signatures

    To test our hypothesis, we used the immunocompetent, transgenic HGG RCAS t-va murine model (NTV-a: Ink4a + /−, Arf + /−, PTEN + /fl, LSL-Luc). Pups…

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  • A chromosome-level genome assembly of the Hermonassa cecilia (Lepidoptera: Noctuidae)

    A chromosome-level genome assembly of the Hermonassa cecilia (Lepidoptera: Noctuidae)

    Sample collection, DNA and RNA extraction

    The sequencing samples of H. cecilia were all male adults, collected through light trapping in October 2023 from the cropland of Xingping City, Xianyang, Shaanxi Province, China. Genomic DNA (gDNA) from a…

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  • H3K27me3 expands the epigenetic control of piRNA transcription

    H3K27me3 expands the epigenetic control of piRNA transcription

    H3K27me3 expands the epigenetic control of piRNA transcription

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  • Cyclic-di-AMP modulates cellular turgor in response to defects in bacterial cell wall synthesis

    Cyclic-di-AMP modulates cellular turgor in response to defects in bacterial cell wall synthesis

  • Oberkampf, M. et al. c-di-AMP signaling is required for bile salt resistance, osmotolerance, and long-term host colonization by Clostridioides difficile. Sci. Signal. 15, eabn8171 (2022).

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    PubMed 
    PubMed Central 

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  • Letter to the editor: Racial differences in serological markers across the first year of injury in spinal cord injury: a retrospective analysis of a multicenter interventional study by Jia Li et al.

  • Li J, Farrow M, Ibrahim K. Racial differences in serological markers across the first year of injury in spinal cord injury: a retrospective analysis of a multi-center interventional study. Spinal Cord. 2024;62:486–94.

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    PubMed 

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  • Is there a link between gut microbes and ageing?

    The Article demonstrating that the microbial metabolite ADP-heptose might be linked to a condition associated with ageing in humans represents a major advance in understanding how microorganisms might contribute to inflammatory diseases of ageing…

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