Category: 5. Biology

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  • Bladder cancer variants share aggressive features including a CA125+ cell state and targetable TM4SF1 expression

    Bladder cancer variants share aggressive features including a CA125+ cell state and targetable TM4SF1 expression

    Sample collection

    All bladder tumor samples used in our analyses were obtained in compliance with ethical regulations under University of California San Francisco IRB 10-04057. Informed consent was obtained from all participants or their legally…

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  • Identification of an immunomodulatory lncRNA signature associated with immune cell reprogramming in high-grade glioma

    Identification of an immunomodulatory lncRNA signature associated with immune cell reprogramming in high-grade glioma

    Analysis of TIME from different glioma models revealed distinct lncRNA signatures

    To test our hypothesis, we used the immunocompetent, transgenic HGG RCAS t-va murine model (NTV-a: Ink4a + /−, Arf + /−, PTEN + /fl, LSL-Luc). Pups…

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